Concept

Photoreceptor cell

Related publications (190)

Precise toxigenic ablation of intermediate cells abolishes the "battery" of the cochlear duct

The extracellular potential of excitable and nonexcitable cells with respect to ground is ∼0 mV. One of the known exceptions in mammals is the cochlear duct, where the potential is ∼80-100 mV, called the endocochlear potential (EP). The EP serves as the "b ...

Society for Neuroscience2013

A polymer optoelectronic interface restores light sensitivity in blind rat retinas

Diego Ghezzi

Interfacing organic electronics with biological substrates offers new possibilities for biotechnology by taking advantage of the beneficial properties exhibited by organic conducting polymers. These polymers have been used for cellular interfaces in severa ...

2013

Autophagy Defect Is Associated with Low Glucose-Induced Apoptosis in 661W Photoreceptor Cells

Johan Auwerx, Pénélope Andreux, Martine Emery

Glucose is an important metabolic substrate of the retina and diabetic patients have to maintain a strict normoglycemia to avoid diabetes secondary effects, including cardiovascular disease, nephropathy, neuropathy and retinopathy. Others and we recently d ...

Public Library of Science2013

Cell shape-dependent early responses of fibroblasts to cyclic strain

Jürgen Brugger, Mattia Marelli

Randomly spread fibroblasts on fibronectin-coated elastomeric membranes respond to cyclic strain by a varying degree of focal adhesion assembly and actin reorganization. We speculated that the individual shape of the cells, which is linked to cytoskeletal ...

Elsevier2013

Modelling 'non-visual' effects of daylighting in a residential environment

Marilyne Andersen, Sharon Jane Gochenour, Steven W. Lockley

The importance of light not only as a therapeutic tool but as an essential element of healthy living has been highlighted by the recent discovery of a specialized photoreceptor in the eye responsible for synchronizing our internal circadian pacemaker. This ...

Elsevier2013

ERK1/2 pathway is activated in degenerated Rpe65-deficient mice

The MAPK family is composed of three majors kinases, JNK, p38 and ERK1/2, and is implicated in many degenerative processes, including retinal cell death. The purpose of our study was to evaluate the activation of ERK1/2 kinase, and its potential role in Mu ...

Academic Press Ltd- Elsevier Science Ltd2013

Self-organisation of motion features with a temporal asynchronous dynamic vision sensor

Neural circuits closer to the periphery tend to be organised in a topological way, i.e. stimuli which are spatially close tend to be mapped onto neighbouring processing neurons. The goal of this study is to show how motion features (optic-flow), which have ...

2013

Whole-Exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-Recessive Complete Congenital Stationary Night Blindness

Congenital stationary night blindness (CSNB) is a heterogeneous retinal disorder characterized by visual impairment under low light conditions. This disorder is due to a signal transmission defect from rod photoreceptors to adjacent bipolar cells in the re ...

2012

Nonvisual light-response model: a preliminary approach to integrating recent findings in biology into a lighting simulation process

Marilyne Andersen, María Lovísa Ámundadóttir, Steven W. Lockley

In addition to stimulating visual responses, light induces a range of circadian, neuroendocrine and neurobehavioral non-visual responses in humans. These effects are mediated primarily via a novel non-rod, non-cone photoreceptor, which is most sensitive to ...

2012

Early apoptosis of rod photoreceptors in Rpe65(-/-) mice is associated with the upregulated expression of lysosomal-mediated autophagic genes

RPE65-related Leber's congenital amaurosis (LCA) is a rod-cone dystrophy whose clinical outcome is mainly attributed to the loss of rod photoreceptors followed by cone degeneration. Pathogenesis in Rpe65-/- mice is characterized by a slow and progressive d ...

2012

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