Concept
Separation axiom
Related publications (14)
Urban sustainability assessment through spatial lenses: turning the spotlight on the local neighbourhood unit
With global environmental change and quality of life issues at the forefront of international discussions today, urban development strategies and policies are often framed around various sustainability or liveability goals. Regardless of the sustainability ...
EPFL2023Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues
Didier Trono, Priscilla Turelli, Julien Léonard Duc, Sandra Eloise Kjeldsen, Marco Cassano, Michaël Imbeault, Gabriela Ecco, Annamaria Kauzlaric, Helen Mary Rowe, Andrea Coluccio
KRAB-containing zinc finger proteins (KRAB-ZFPs) are early embryonic controllers of transposable elements (TEs), which they repress with their cofactor KAP1 through histone and DNA methylation, a process thought to result in irreversible silencing. Using a ...
Cell Press2016Unraveling the KRAB/KAP1 control of transposable elements in pluripotent and somatic cells
Transposable elements (TEs) are DNA sequences able to change position in the genome, and represent more than 40% of mammalian genetic material. TEs can have positive or detrimental effects on the host, being both important motors of evolution and genomic t ...
EPFL2016