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An important principle of human ethics is that individuals are not responsible for actions performed when unconscious. Recent research found that the generation of an action and the building of a conscious experience of that action (agency) are distinct pr ...
Amperometric biosensors are complex systems and they require a combination of technologies for their development. The aim of the present work is to exploit existing technologies for new purposes in order to develop nanostructured biosensors for the real-ti ...
The potential of agent-based modeling (ABM) has been demonstrated in various research fields. However, three major concerns limit the full exploitation of ABM; (i) agents are too simple and behave unrealistically without any empirical basis, (ii) 'proof of ...
Brain imaging has shown altered corpus callosum (CC) morphology in patients with Gilles de la Tourette syndrome (GTS). Yet it is unclear whether these morphological changes are associated with altered interhemispheric interactions. Here, we combined transc ...
Activation volumes characteristic of room temperature compressive plastic deformation in Au- 45.2 at.% Cu- 1.7 at.% Pt, a near-AuCu alloy that orders to a fully L1(0) structure, are measured using the repeated stress-relaxation method. Four different order ...
This thesis investigates nine new compositions of the ternary Au-Cu-Pt system, containing from 75 to 78 wt% Au with 0 to 15 wt% Pt, by means of in-situ synchrotron radiation X-ray diffraction, differential scanning calorimetry, transmission electron micros ...
It is estimated that the Maoist conflict has created 250,000 Internally Displaced Persons (IDPs) in Nepal. The livelihood questions of these IDPs are crucial to the state. However, knowledge on the livelihoods of these IDPs has mostly been derived from sho ...
Gamma-secretase is an intramembrane-cleaving protease responsible for the final proteolytic event in the production of the amyloid-beta peptides (Abeta) implicated in Alzheimer's disease (AD). Inhibition of gamma-secretase activity is thus an attractive th ...
The crystal structure of bis(tetra-n-butylammonium)bis(mu(2)-hydroxo)-bis(1,2,3,4-tetrakis(methoxycarbonyl)-1,3-butadiene-1,4-diyl)-di-palladium, NBu4[Pd-2{C-4(COOMe)(4)}(2) (mu-OH)(2)], was determined ab initio by X-ray single-crystal diffractometry ...
The ageing of existing structures and new innovative designs are increasing the necessity for a greater understanding of structural behaviour. A better understanding would improve effectiveness of activities such as assessing reserve capacity, evaluating l ...