Concept

Electrical synapse

Related publications (94)

The Target of Exuberant Projections in Development

In addition to neuronal death and elimination of synapses, the production of transient, exuberant axons, and axonal branches is a general phenomenon in development across species and systems. To understand what drives the decision of which axons are mainta ...

2020

Dense Computer Replica of Cortical Microcircuits Unravels Cellular Underpinnings of Auditory Surprise Response

Henry Markram, Eilif Benjamin Muller, Srikanth Ramaswamy, Michael Reimann, James Gonzalo King, Oren Amsalem, Idan Segev

The nervous system is notorious for its strong response evoked by a surprising sensory input, but the biophysical and anatomical underpinnings of this phenomenon are only partially understood. Here we utilized in-silico experiments of a biologically-detail ...

2020

Double-gate field-effect-transistor based biosensor

Hoël Maxime Guérin

The present invention concerns a biosensor (1) comprising: a source element (13); a drain element (17); a semiconductor channel element between the source element (13) and the drain element (17) for forming an electrically conductive channel with adjustabl ...

2019

Experimentally-constrained biophysical models of tonic and burst firing modes in thalamocortical neurons

Henry Markram, Sean Lewis Hill, Werner Alfons Hilda Van Geit, Ying Shi, Christian O'Reilly, Christian Andreas Rössert, Elisabetta Iavarone, Bas-Jan Zandt, Jane Yi

Somatosensory thalamocortical (TC) neurons from the ventrobasal (VB) thalamus are central components in the flow of sensory information between the periphery and the cerebral cortex, and participate in the dynamic regulation of thalamocortical states inclu ...

2019

Spatiotemporal Imaging of Water in Operating Voltage-Gated Ion Channels Reveals the Slow Motion of Interfacial Ions

Sylvie Roke, Aleksandra Radenovic, Orly Bagunu Tarun, Maksim Eremchev

Ion channels are responsible for numerous physiological functions ranging from transport to chemical and electrical signaling. Although static ion channel structure has been studied following a structural biology approach, spatiotemporal investigation of t ...

2019

Black Lipid Membranes: Challenges in Simultaneous Quantitative Characterization by Electrophysiology and Fluorescence Microscopy

Esther Amstad, Stefan Matile, Maria Tsemperouli

Horizontal black lipid membranes (BLMs) enable optical microscopy to be combined with the electrophysiological measurements for studying ion channels, peptide pores, and ionophores. However, a careful literature review reveals that simultaneous fluorescenc ...

AMER CHEMICAL SOC2019

First Biopotential Recordings from a Liquid Crystal Optrode

Han Wang

One of the goals of the Neural Engineering System Design (NESD) program in the United States and of similar programs around the world is to develop an interface able to read from one million neurons in parallel. This is well beyond the capabilities of trad ...

SPIE-INT SOC OPTICAL ENGINEERING2019

Nonlinear microscopy for temporally and spatially resolved label-free imaging of living cells

Marie Eve Pascale Didier

The human brain consists of approximately a hundred billion of neurons that communicate through a unique series of biochemical and electrical processes. When neuronal networks are solicited, electrochemical processes happen involving millions of cells with ...

EPFL2018

Intrafascicular electrode implant

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

An implantable device for intrafascicular stimulation and/or sensing of a peripheral nerve, including a blocking element adapted for wrapping a nerve, comprising an access point and an exit point, and an electrode adapted to traverse the blocking element v ...

2018

An Efficient Electronic Measurement Interface for Memristive Biosensors

Giovanni De Micheli, Sandro Carrara, Pierre-Emmanuel Julien Marc Gaillardon, Ioulia Tzouvadaki, Armando Biscontini, Sébastien Naus

Reducing sensing time is one major concern in clinical diagnostics. In the present work, a robust measurement system is developed aiming at the faster and easier signal acquisition of memristive biosensors. Sensing chips consisting of nanofabricated silico ...

IEEE2017

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