Concept
Neuromodulation
Related publications (102)
A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits
Information is transmitted between brain regions through the release of neurotransmitters from long-range projecting axons. Understanding how the activity of such long-range connections contributes to behavior requires efficient methods for reversibly mani ...
Nature Portfolio2024Fear learning induces synaptic potentiation between engram neurons in the rat lateral amygdala
Henry Markram, Rodrigo de Campos Perin
The lateral amygdala (LA) encodes fear memories by potentiating sensory inputs associated with threats and, in the process, recruits 10-30% of its neurons per fear memory engram. However, how the local network within the LA processes this information and w ...
Nature Portfolio2024GABAergic-like dopamine synapses in the brain
Dopamine synapses play a crucial role in volitional movement and reward-related behaviors, while dysfunction of dopamine synapses causes various psychiatric and neurological disorders. Despite this significance, the true biological nature of dopamine synap ...
Cambridge2023Bioaccumulation and molecular effects of carbamazepine and methylmercury co-exposure in males of Dreissena polymorpha
Florian Frédéric Vincent Breider, Dominique Grandjean, Nguyên Thiên Kim Lê, Claudia Cosio
Dreissena polymorpha is a bivalve promising for biomonitoring in freshwater ecosystems thanks to its abundance and high filtration activity allowing rapid uptake of toxicants and identification of their negative effects. Nonetheless, we still lack knowledg ...
2023Membrane potential dynamics of excitatory and inhibitory neurons in mouse barrel cortex during active whisker sensing
Carl Petersen, Sylvain Crochet, Aurélie Pala, Taro Kiritani, Célia Roxane Gasselin
Neocortical neurons can increasingly be divided into well-defined classes, but their activity patterns during quantified behavior remain to be fully determined. Here, we obtained membrane potential recordings from various classes of excitatory and inhibito ...
PUBLIC LIBRARY SCIENCE2023Neuromodulation of neocortical microcircuitry: a multi-scale framework to model the effects of cholinergic release
Neuromodulation of neocortical microcircuits is one of the most fascinatingand mysterious aspects of brain physiology. Despite over a century of research,the neuroscientific community has yet to uncover the fundamentalbiological organizing principles under ...
EPFL2022