Paul-Félix Armand-Delille

Paul-Félix Armand-Delille (3 July 1874 – 4 September 1963) was a French physician, bacteriologist, professor, and member of the French Academy of Medicine. He is best known for attempting to protect his crop from rabbits by releasing a pair of rabbits infected with Myxoma virus on to his farm in northern France. The spread of the vira lead to a plague of myxomatosis that caused the collapse of rabbit populations throughout much of Europe and beyond in the 1950s. Born in Fourchambault, Nièvre, in central France, Armand-Delille studied medicine and became a professor at the Paris School of Medicine, specialising in infectious diseases in children. During the First World War he carried out important work on malaria, for which he was made a Commander of the Legion of Honour. He later retired. Having read of the effectiveness of the myxomatosis virus in dealing with rabbit plagues in Australia, in 1952 Armand-Delille decided to intentionally introduce the virus onto his private estate of Chateau Maillebois in Eure-et-Loir, not far from Paris. He used a strain of the virus, which had been isolated in 1949 and believed that the enclosed nature of the estate would prevent its spread into other rabbit populations. Inoculating two rabbits with Myxoma virus acquired from a laboratory in Lausanne, Armand-Delille succeeded in rapidly eradicating the population on his estate, with 98% of the rabbits being dead within six weeks. However, within four months it became clear that the virus had escaped from his estate, the corpse of an infected rabbit having been found 50 km (30 miles) away. Within a year of the initial release, an estimated 45% of the wild rabbits in France had died of the disease, along with 35% of domestic rabbits, and the disease subsequently spread to the rest of western Europe, destroying rabbit populations in the Netherlands, Belgium, Italy, Spain, Germany, Britain, and beyond. The effect on the rabbit population of France was dramatic.