Concept

History of penicillin

Related publications (11)

Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa

P. aeruginosa (PA) continues to pose a threat to global public health due to its high levels of antimicrobial resistance (AMR). The ongoing AMR crisis has led to an alarming shortage of effective treatments for resistant microbes, and hence there is a pres ...

AMER CHEMICAL SOC2021

Catalytic and antibacterial properties of 3-dentate carboxamide Pd/Pt complexes obtained via a benign route

Kurt Schenk, Farzaneh Fadaei Tirani

The complexes Pd-II(qcq)(OAc) and Pt-II(qcq)Cl have been synthesized using environmentally benign synthesized ligands and characterized by elemental analyses: Fourier transform infrared spectroscopy, UV-visible spectroscopy, H-1 NMR spectroscopy, and X-ray ...

WILEY2020

Digitally Printed AgNPs Doped TiO2 on Commercial Porcelain-Grès Tiles: Synergistic Effects and Continuous Photocatalytic Antibacterial Activity

Sami Rtimi

In the present study, we use commercial digitally printed ceramic tiles, functionnalized by AgNPs doped micro–TiO2, to investigate the mechanism of Ag in the continouos photocatalytic antibacterial activity. The novelty of the research lies in the attempt ...

2020

OprD Repression upon Metal Treatment Requires the RNA Chaperone Hfq in Pseudomonas aeruginosa

Rodrigo Manuel Gonzalez, Tiziana Scrignari

The metal-specific CzcRS two-component system in Pseudomonas aeruginosa is involved in the repression of the OprD porin, causing in turn carbapenem antibiotic resistance in the presence of high zinc concentration. It has also been shown that CzcR is able t ...

Mdpi Ag2016

Inactivation of Antibiotic Resistant Bacteria and Resistance Genes by Ozone: From Laboratory Experiments to Full-Scale Wastewater Treatment

Urs von Gunten, Nadine Czekalski, Helmut Bürgmann

Ozone, a strong oxidant and disinfectant, seems ideal to cope with future challenges of water treatment, such as micropollutants, multiresistant bacteria (MRB) and even intracellular antibiotic resistance genes (ARG), but information on the latter is scarc ...

American Chemical Society2016

Rapid detection of bacterial resistance to antibiotics using AFM cantilevers as nanomechanical sensors

Giovanni Dietler, Sandor Kasas, Giovanni Longo, Livan Bladimir Alonso Sarduy, Laura Rio Marques, Justin Terence Notz Pekkanen

The widespread misuse of drugs has increased the number of multiresistant bacteria1, and this means that tools that can rapidly detect and characterize bacterial response to antibiotics are much needed in the management of infections. Various techniques, s ...

Nature Publishing Group2013

Sources, Spreading and Fate of Antibiotic Resistance Genes and Resistant Bacteria in Vidy Bay, Lake Geneva, Switzerland

Nadine Czekalski

Increasing numbers of multiresistant bacterial pathogens cause severe health problems on a global scale. Large quantities of bacteria and their resistance genes are discharged into natural environments via human and animal waste. Not much is known so far a ...

EPFL2013

Seasonal variations of antibiotics measured in the environment from sales data analysis

Luca Rossi, Sylvain Coutu, Jonas Margot, Christa McArdell

Antibiotics are substances commonly consumed by the population under medical prescriptions. These compounds may reach the environment through human excretion as they are partially eliminated in WWTPs. The occurrence of antibiotics in the aquatic environmen ...

2011

Preparation of aminoacylated tRNAs and analogues

The ribosome-mediated, site-specific incorporation of unnatural amino acids into proteins is a powerful tool for creating protein analogues with specific steric, chemical, electronic or spectroscopic properties, in vitro and in vivo. The required aminoacyl ...

EPFL2006

Identification and overexpression in Escherichia coli of a Mycobacterium leprae gene, pon1, encoding a high-molecular-mass class A penicillin-binding protein, PBP1.

Stewart Cole

Cosmid B577, a member of the collection of ordered clones corresponding to the genome of Mycobacterium leprae, contains a gene, provisionally called pon1, that encodes an 821-amino-acid-residue high-molecular-mass class A penicillin-binding protein, provis ...

1996

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