Concept

Homeotic protein bicoid

Related publications (5)

Engineered signaling centers for the spatially controlled patterning of human pluripotent stem cells

Matthias Lütolf, Felix Naef, Yoji Tabata, Eric Paquet, François Réal Rivest, Ambroise Roger Vuaridel, Andrea Manfrin

Signaling centers, localized groups of cells that secrete morphogens, play a key role in early development and organogenesis by orchestrating spatial cell fate patterning. Here we present a microfluidic approach that exposes human pluripotent stem cell (hP ...

NATURE PUBLISHING GROUP2019

The primary stability of cementless femoral components is crucial for the long-term success of total hip arthroplasty. We know that the healing phase after surgery is a complex biological process, which is affected by the mechanical environment. Implant lo ...

EPFL2011

Morphogens are secreted molecules that influence the fate of neighboring cells in a concentration-dependant manner. For this reason, their distribution and diffusion strongly influence their roles. In my master thesis, I focused on a posttranslational modi ...

2008

Tissue morphogenesis and remodeling is often orchestrated by cell-secreted proteins, referred to as morphogens that can trigger cellular responses in addition to modifying the local extracellular matrix (ECM). Of specific interest is the distribution of ce ...

EPFL2007

Synergy between interstitial flow and VEGF directs capillary morphogenesis in vitro through a gradient amplification mechanism

Melody Swartz, Federica Boschetti, Mark Fleury

Cell organization is largely orchestrated by extracellular gradients of morphogenetic proteins. VEGF, an essential factor for capillary formation, is stored in the extracellular matrix, but the mechanisms by which it and other matrix-bound morphogens are m ...

2005

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