Concept
Photomedicine
Related publications (11)
Photodynamic Therapy Selectively Enhances Liposomal Doxorubicin Uptake in Sarcoma Tumors to Rodent Lungs
Hubert van den Bergh, Georges Wagnières, Elodie Debefve, Laurent Décosterd
Background: In specific conditions, photodynamic therapy (PDT) can enhance the distribution of macromolecules across the endothelial barrier in solid tumors. It was recently postulated that tumor neovessels were more responsive to PDT than the normal vascu ...
Wiley-Blackwell2010Photodynamic therapy induces selective extravasation of macromolecules: Insights using intravital microscopy
Hubert van den Bergh, Elodie Debefve
Photodynamic therapy (PDT) with Visudyne acts by direct cellular phototoxicity and/or by an indirect vascular-mediated effect. Here, we demonstrate that the vessel integrity interruption by PDT can promote the extravasation of a macromolecular agent in nor ...
Elsevier2010Combination therapy using aspirin-enhanced photodynamic selective drug delivery
Hubert van den Bergh, Elodie Debefve
In photodynamic therapy (PDT), excitation of a drug by light leads to a cascade of biochemical processes that can cause closure of blood vessels. It has been observed clinically that significant short-term leakage from the irradiated vasculature can occur ...
Elsevier2007