Related publications (14)

Benchmarking informatics approaches for virus discovery: caution is needed when combining in silico identification methods

Jaspreet Singh Saini

Understanding the ecological impacts of viruses on natural and engineered ecosystems relies on the accurate identification of viral sequences from community sequencing data. To maximize viral recovery from metagenomes, researchers frequently combine viral ...
Washington2024

Viral Genetic Determinants of Prolonged Respiratory Syncytial Virus Infection Among Infants in a Healthy Term Birth Cohort

Jacques Fellay, Zhi Ming Xu, Dylan Lawless, Thomas Junier

Background. Respiratory syncytial virus (RSV) is associated with acute respiratory infection. We sought to identify RSV variants associated with prolonged infection. Methods. Among healthy term infants we identified those with prolonged RSV infection and c ...
OXFORD UNIV PRESS INC2023

DeepBreath-automated detection of respiratory pathology from lung auscultation in 572 pediatric outpatients across 5 countries

Martin Jaggi, Mary-Anne Hartley, Juliane Dervaux, Tatjana Chavdarova, Daniel Mueller, Julien Niklas Heitmann, Daniel Hinjos García

The interpretation of lung auscultation is highly subjective and relies on non-specific nomenclature. Computer-aided analysis has the potential to better standardize and automate evaluation. We used 35.9 hours of auscultation audio from 572 pediatric outpa ...
NATURE PORTFOLIO2023

Roles of Clinical Features and Chest CT in Predicting the Outcomes of Hospitalized Patients with COVID-19 Developing AKI

Ali Falsafi, Shekoofeh Yaghmaei

This research aimed to evaluate the clinical features and computed tomography (CT) scans associated with poor outcomes in COVID-19 patients with acute kidney injury (AKI). A total of 351 COVID-19 patients (100 AKI, 251 non-AKI) hospitalized at Imam Hossein ...
IRANIAN SOC NEPHROLGY2023

Novel trehalose-based excipients for stabilizing nebulized anti-SARS-CoV-2 antibody

Sandrine Gerber, François Rémi Pierre Noverraz, Solène Marcelle Françoise Marie Passemard

COVID-19 is caused by the infection of the lungs by SARS-CoV-2. Monoclonal antibodies, such as sotrovimab, showed great efficiency in neutralizing the virus before its internalization by lung epithelial cells. However, parenteral routes are still the prefe ...
2022

Using soft aerosolization and sampling techniques for the conservation of virus infectivity during airborne exposure experiments

Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David

Recurrent epidemic outbreaks such as the seasonal flu and the ongoing COVID-19 are disastrous events to our societies both in terms of fatalities, social and educational structures, and financial losses. The difficulty to control their spread and minimize ...
2021

Functional de novo Protein Design for Targeted Vaccines and Synthetic Biology Applications

Che Yang

Evolution has created, selected and evolved large repertoires of proteins that operate in various biological systems. Nowadays biotechnological needs are coming up orders of magnitude faster than proteins naturally evolve. The emergence of de novo protein ...
EPFL2020

Relative Effects of the Hospital Readmissions Reduction Program on Hospitals That Serve Poorer Patients

Yun Wang, Christine Choirat

Importance: Hospitals that serve poorer populations have higher readmission rates. It is unknown whether these hospitals effectively lowered readmission rates in response to the Hospital Readmissions Reduction Program (HRRP). Objective: To compare pre-post ...
2019

Pepper mild mottle virus as a water quality indicator

Pepper mild mottle virus (PMMoV) was recently found to be the most abundant RNA virus in human feces, and is a plant virus belonging to the genus Tobamovirus in the family Virgoviridae. When in human feces, it is of dietary origin from peppers and their pr ...
NATURE PUBLISHING GROUP2018

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

Eva Sabrina Gollwitzer, Nicola Harris, Benjamin John Marsland

BACKGROUND: Helminth parasites have been reported to have beneficial immunomodulatory effects in patients with allergic and autoimmune conditions and detrimental consequences in patients with tuberculosis and some viral infections. Their role in coinfectio ...
Elsevier2017

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.