Neocortex

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Neuroanatomy

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Hippocampal Contribution to Ordinal Psychological Time in the Human Brain

Baptiste Gauthier

The chronology of events in time-space is naturally available to the senses, and the spatial and temporal dimensions of events entangle in episodic memory when navigating the real world. The mapping of time-space during navigation in both animals and human ...

MIT PRESS2020

An overlapping pattern of cerebral cortical thinning is associated with both positive symptoms and aggression in schizophrenia via the ENIGMA consortium

Erick Jorge Canales Rodriguez, Wenhao Jiang

Background Positive symptoms are a useful predictor of aggression in schizophrenia. Although a similar pattern of abnormal brain structures related to both positive symptoms and aggression has been reported, this observation has not yet been confirmed in a ...

2020

Objective Morphological Classification of Neocortical Pyramidal Cells

Henry Markram, Kathryn Hess Bellwald, Srikanth Ramaswamy, Rodrigo de Campos Perin, Lida Kanari, Ying Shi, Julie Meystre, Marwan Muhammad Ahmed Abdellah, Yun Wang

A consensus on the number of morphologically different types of pyramidal cells (PCs) in the neocortex has not yet been reached, despite over a century of anatomical studies, due to the lack of agreement on the subjective classifications of neuron types, w ...

Oxford University Press (OUP)2019

A null model of the mouse whole-neocortex micro-connectome

Henry Markram, Eilif Benjamin Muller, Michael Reimann, Ying Shi, Huanxiang Lu

In connectomics, the study of the network structure of connected neurons, great advances are being made on two different scales: that of macro- and meso-scale connectomics, studying the connectivity between populations of neurons, and that of micro-scale c ...

Nature Research2019

Estimating the Readily-Releasable Vesicle Pool Size at Synaptic Connections in the Neocortex

Henry Markram, Eilif Benjamin Muller, Srikanth Ramaswamy, Rodrigo de Campos Perin, Giuseppe Chindemi, Natali Barros Zulaica

Previous studies based on the 'Quantal Model' for synaptic transmission suggest that neurotransmitter release is mediated by a single release site at individual synaptic contacts in the neocortex. However, recent studies seem to contradict this hypothesis ...

2019

Optical sensory and motor mapping of mouse dorsal cortex

Matthieu Pierre Auffret

Throughout species, including mice and humans, we all have to make decisions to fulfill our fundamentals needs: eat, drink, explore, communicate, reproduce... To make those decisions, we have to collect informations from the surrounding world and to proces ...

EPFL2018

Two-photon calcium imaging of neocortical projection neurons in whisker somatosensory cortex during goal-directed sensorimotor learning

Dimitra Angeliki Vavladeli

Excitatory projection neurons of the neocortex are thought to play important roles in perceptual and cognitive functions of the brain by directly connecting diverse cortical and subcortical areas. However, many aspects of the anatomical and functional orga ...

EPFL2018

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An overlapping pattern of cerebral cortical thinning is associated with both positive symptoms and aggression in schizophrenia via the ENIGMA consortium

Erick Jorge Canales Rodriguez, Wenhao Jiang

2020

Estimating the Readily-Releasable Vesicle Pool Size at Synaptic Connections in the Neocortex

Henry Markram, Eilif Benjamin Muller, Srikanth Ramaswamy, Rodrigo de Campos Perin, Giuseppe Chindemi, Natali Barros Zulaica

2019

Optical sensory and motor mapping of mouse dorsal cortex

Matthieu Pierre Auffret

EPFL2018

Two-photon calcium imaging of neocortical projection neurons in whisker somatosensory cortex during goal-directed sensorimotor learning

Dimitra Angeliki Vavladeli

EPFL2018