Concept

Allostatic load

Related publications (15)

Identification of biopsychological trait markers in functional neurological disorders

Weber et al. provide evidence in support of a stress-diathesis model of functional neurological disorders. They identify trauma history in the form of emotional neglect as a psychological risk factor, and reduced hippocampus and amygdala volume as a predis ...

OXFORD UNIV PRESS2022

Extended gate field-effect-transistor for sensing cortisol stress hormone

Mihai Adrian Ionescu, Junrui Zhang, Sadegh Kamaei Bahmaei, Hoël Maxime Guérin, Luca Capua, Shokoofeh Sheibani, Sayedeh Shirin Afyouni Akbari

Cortisol is a hormone released in response to stress and is a major glucocorticoid produced by adrenal glands. Here, we report a wearable sensory electronic chip using label-free detection, based on a platinum/graphene aptamer extended gate field effect tr ...

SPRINGERNATURE2021

Are Pre-ascent Low-Altitude Saliva Cortisol Levels Related to the Subsequent Acute Mountain Sickness Score? Observations from a Field Study

Johannes Burtscher

Background: The associations among cortisol levels, body water status, and acute mountain sickness (AMS) remain unclear. We investigated associations between AMS prevalence and severity with resting saliva cortisol levels at low altitude (LA) and high alti ...

MARY ANN LIEBERT, INC2019

An energetic view of stress: Focus on mitochondria

Maria del Carmen Sandi Perez

Energy is required to sustain life and enable stress adaptation. At the cellular level, energy is largely derived from mitochondria – unique multifunctional organelles with their own genome. Four main elements connect mitochondria to stress: 1) Energy is r ...

2018

Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis

Johan Auwerx, Dongryeol Ryu

Reduced mitochondria! electron transport chain activity promotes longevity and improves energy homeostasis via cell-autonomous and non-autonomous factors in multiple model systems. This mitohormetic effect is thought to involve the mitochondrial unfolded p ...

Rockefeller Univ Press2017

Phenotypic Heterogeneity in Mycobacterium tuberculosis

John McKinney, Neeraj Dhar, Giulia Manina

The interaction between the host and the pathogen is extremely complex and is affected by anatomical, physiological, and immunological diversity in the microenvironments, leading to phenotypic diversity of the pathogen. Phenotypic heterogeneity, defined as ...

Amer Soc Microbiology2016

Effect on Bridge Load Effects of Vehicle Transverse In-Lane Position: A Case Study

Mark Anthony Treacy

This paper presents an investigation of the influence of vehicle transverse in-lane position on bridge traffic load effects. To analyze the influence, both finite-element analysis and statistical analysis methods are used, and various technical aspects are ...

American Society of Civil Engineers2015

Aspects of Arterial Wall Simulations: Nonlinear Anisotropic Material Models and Fluid Structure Interaction

Alfio Quarteroni, Simone Deparis, Davide Forti

The simulation of the physiological loading situation of arteries with moderate atherosclerotic plaque may provide additional indicators for medical doctors to estimate if the plaque is likely to rupture and if surgical intervention is required. In particu ...

International Center for Numerical Methods in Engineeering (CIMNE)2014

Mechanical Characterization and Shape Optimization of Fascicle-Like 3D Skeletal Muscle Tissues Contracted with Electrical and Optical Stimuli

Mahmut Selman Sakar

In this study, we present a quantitative approach to construct effective 3D muscle tissues through shape optimization and load impedance matching with electrical and optical stimulation. We have constructed long, thin, fascicle-like skeletal muscle tissue ...

2014

Rock fragmentation mechanism by TBM cutter and TBM tunnelling under stressed grounds

Lijun Yin

With the advance of technology, TBMs are becoming more versatile and TBM tunnelling has become a common tunnelling method. As TBM tunnelling is a special excavation method depending on the interaction between machine and rock mass under a certain geologica ...

EPFL2013

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