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Covers the design and analysis of inhibitors for next-generation covalent drugs, focusing on target engagement and the importance of cysteine targeting.
Explores protein folding, amino acids, RNA translation, and attractive forces, emphasizing the importance of native state conformation and compact structures.
Explores post-translational modifications and folding processes in the endoplasmic reticulum, using examples like the influenza virus and protein misfolding diseases.
Explores covalent lipid modifications of proteins and their role in protein-membrane interactions, including the biochemistry of membrane proteins and the challenges of studying them.