Publications related to Hyperammonemia

High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica

Henning Paul-Julius Stahlberg, Jasenko Zivanov

Urease converts urea into ammonia and carbon dioxide and makes urea available as a nitrogen source for all forms of life except animals. In human bacterial pathogens, ureases also aid in the invasion of acidic environments such as the stomach by raising th ...

2020

Ammonia toxicity: from head to toe?

Peter Ott, Veronika Rackayová

Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues. It is known that the toxic ramifications of ammonia primarily touch the brain and cause neurologica ...

Springer Verlag2017

Ammonia toxicity to the brain

Cristina Ramona Cudalbu

Hyperammonemia can be caused by various acquired or inherited disorders such as urea cycle defects. The brain is much more susceptible to the deleterious effects of ammonium in childhood than in adulthood. Hyperammonemia provokes irreversible damage to the ...

Springer Verlag2013

Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopy

Rolf Gruetter, Cristina Ramona Cudalbu, Bernard Lanz, Yves Pilloud, João Miguel das Neves Duarte

Brain glutamine synthetase (GS) is an integral part of the glutamate-glutamine cycle and occurs in the glial compartment. In vivo Magnetic Resonance Spectroscopy (MRS) allows noninvasive measurements of the concentrations and synthesis rates of metabolites ...

Nature Publishing Group2012

Batch cultures of a hybridoma cell line performed with in situ ammonia removal

Urs von Stockar, Ian William Marison, Markus Schneider

Batch cultures of a mouse/mouse hybridoma cell line secreting a dimeric IgA were performed in combination with a membrane process for the continuous removal of ammonia from the culture medium. The latter involves hydrophobic porous membranes with an assocd ...

1997

High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica

Henning Paul-Julius Stahlberg, Jasenko Zivanov

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Hyperammonemia

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica

Ammonia toxicity: from head to toe?

Ammonia toxicity to the brain

Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopy

Batch cultures of a hybridoma cell line performed with in situ ammonia removal

High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica

Graph Chatbot

Chat with Graph Search

Ammonia toxicity: from head to toe?

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Ammonia toxicity to the brain

High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica

High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica

Batch cultures of a hybridoma cell line performed with in situ ammonia removal

Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopy