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Claustrum

Related publications (128)

Neuronal correlates of goal-directed sensorimotor transformation in sensory, motor and higher-order cortical areas

An important function of the brain is to interpret incoming sensory information from the outside world to guide adaptive behavior. Understanding how and where sensory information is transformed into motor commands in a context- and learning-dependent manne ...

EPFL2023

Membrane potential dynamics of excitatory and inhibitory neurons in mouse barrel cortex during active whisker sensing

Carl Petersen, Sylvain Crochet, Aurélie Pala, Taro Kiritani, Célia Roxane Gasselin

Neocortical neurons can increasingly be divided into well-defined classes, but their activity patterns during quantified behavior remain to be fully determined. Here, we obtained membrane potential recordings from various classes of excitatory and inhibito ...

PUBLIC LIBRARY SCIENCE2023

A parcellation scheme of mouse isocortex based on reversals in connectivity gradients

Michael Reimann

The brain is composed of several anatomically clearly separated structures. This parcellation is often extended into the isocortex, based on anatomical, physiological or functional differences. Here, we derive a parcellation scheme based purely on the spat ...

2023

Structure-function coupling increases during interictal spikes in temporal lobe epilepsy: A graph signal processing study

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Patric Hagmann

Objective: Structure-function coupling remains largely unknown in brain disorders. We studied this coupling during interictal epileptic discharges (IEDs), using graph signal processing in temporal lobe epilepsy (TLE). Methods: We decomposed IEDs of 17 pati ...

ELSEVIER IRELAND LTD2023

Of mice and men: Increased dendritic complexity gives rise to unique human networks

Henry Markram, Kathryn Hess Bellwald, Lida Kanari, Alexis Arnaudon, Ying Shi, Jay Coggan, Natali Barros Zulaica, Idan Segev, Ruth Benavides Piccione

The organizational principles that distinguish the human brain from those of other species have been a long-standing enigma in neuroscience. Here, we leverage advances in algebraic topology to uncover the structural properties of the human brain at subcell ...

bioRxiv2023

Learning-related congruent and incongruent changes of excitation and inhibition in distinct cortical areas

Carl Petersen, Sylvain Crochet, Romain Guiet, Vahid Esmaeili, Yanqi Liu, Georgios Foustoukos, Keita Tamura, Anastasiia Oryshchuk, Reza Asri

Excitatory and inhibitory neurons in diverse cortical regions are likely to contribute differentially to the transformation of sensory information into goal-directed motor plans. Here, we investigate the relative changes across mouse sensorimotor cortex in ...

2022

Modeling and simulation of rat non-barrel somatosensory cortex. Part I: Modeling anatomy

Matthias Wolf, Henry Markram, Kathryn Hess Bellwald, Felix Schürmann, Eilif Benjamin Muller, Srikanth Ramaswamy, Michael Reimann, Daniel Keller, Werner Alfons Hilda Van Geit, James Gonzalo King, Lida Kanari, Pramod Shivaji Kumbhar, Alexis Arnaudon, Ying Shi, Jean-Denis Georges Emile Courcol, Armando Romani, András Ecker, Michael Emiel Gevaert, Cyrille Pierre Henri Favreau, Vishal Sood, Sirio Bolaños Puchet, James Bryden Isbister, Judit Planas Carbonell, Daniela Egas Santander, Christoph Pokorny, Adrien Michel Achille Devresse, Gianluca Ficarelli, Hugo Thabo Dictus, Janis Lazovskis, Juan Bautista Hernando Vieites, Huanxiang Lu, Liesbeth Maria L Vanherpe, Ran Levi, Joni Henrikki Herttuainen, Samuel Lieven D. Lapere, Juan Luis Riquelme Roman, Thomas Brice Delemontex, Nicolas René Jean Ninin, Alexander Dietz, Benoît Jean-Albert Coste

The function of the neocortex is fundamentally determined by its repeating microcircuit motif, but also by its rich, hierarchical, interregional structure with a highly specific laminar architecture. The last decade has seen the emergence of extensive new ...

2022

Cortical sensory processing across motivational states during goal-directed behavior

Carl Petersen, Georgios Foustoukos, Matthieu Pierre Auffret, Sami El-Boustani, Johannes Maria Mayrhofer, Maëlle Guyoton

Behavioral states can influence performance of goal-directed sensorimotor tasks. Yet, it is unclear how altered neuronal sensory representations in these states relate to task performance and learning. We trained water-restricted mice in a two-whisker disc ...

2022

Simulating the progression of brain structural alterations in Parkinson's disease

Chang-Hyun Park

Considering brain structural alterations as neurodegenerative consequences of Parkinson's disease (PD), we sought to infer the progression of PD via the ordering of brain structural alterations from cross-sectional MRI observations. Having measured cortica ...

NATURE PORTFOLIO2022

Neuromodulatory organization in the developing rat somatosensory cortex

Henry Markram, Srikanth Ramaswamy, Armando Romani, Cristina Colangelo, Alberto Antonietti, Joni Henrikki Herttuainen

The vast majority of cortical synapses are found in the neuropil which is implicated in multiple and diverse functions underlying brain computation. Unraveling the organizing principles of the cortical neuropil requires an intricate characterization of syn ...

2022

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