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Biological cells modulate their behavior, express genes, proliferate or differentiate in response to mechanical strains ranging from 1% to 20%. There currently exists no technique to apply strain to many targeted individual cells in a larger culture in ord ...
Biomolecules are the building blocks of living organisms and perform the most important functions in a biological process. The aim of biophysics is to understand the biological functions of biomolecules in terms of their structure: structure and function o ...
Over the last decade, ultrafast time-resolved X-ray absorption spectroscopy (XAS) has evolved to be now a mature and well-established experimental technique, giving extremely detailed information about the local geometrical and electronic structure in the ...
Living organisms consist of cells, the elementary components of which are proteins providing cellular structures and functionality. Nowadays, proteins of the size of one to a few tens of nanometers can be efficiently monitored by fluorescence microscopy an ...
Recent developments in single-molecule localization techniques using photoactivatable fluorescent proteins have allowed the probing of single-molecule motion in a living cell with high specificity, millisecond time resolution, and nanometer spatial resolut ...
The second harmonic generation (SHG) active nanocrystals have been demonstrated as attractive imaging probes in nonlinear microscopy due to their coherent, non-bleaching and non-blinking signals with a broad flexibility in the choice of excitation waveleng ...
Experimental techniques in molecular biology have led to the production of enormous amounts of data on the dynamics of cellular processes. The availability of time series data characterizing genomic, proteomic and metabolic systems must be complemented wit ...
The generation of robust periodic movements of complex nonlinear robotic systems is inherently difficult, especially, if parts of the robots are compliant. It has previously been proposed that complex nonlinear features of a robot, similarly as in biologic ...
Biological cells regulate their biochemical behavior in response to mechanical stress present in their organism. Most of the available cell cultures designed to study the effect of mechanical stimuli on cells are cm2 area, far too large to monitor single c ...
Nanoparticles that activate complement in the absence of biological molecules are described. The nanoparticles are shown to specifically target antigen presenting cells in specifically in lymph nodes, without the use of a biological molecule for targeting. ...
