Concept

Muscle cell

Related publications (331)

Enhanced Respiratory Chain Supercomplex Formation in Response to Exercise in Human Skeletal Muscle

Johan Auwerx, Carlos Canto Alvarez, Xu Wang, Pooja Jha, Chiara Greggio

Mitochondrial dysfunction is a hallmark of multiple metabolic complications. Physical activity is known to increase mitochondrial content in skeletal muscle, counteracting age-related decline in muscle function and protecting against metabolic and cardiova ...

Cell Press2017

Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro

Jonathan Paz Montoya, Marc Moniatte, Frédéric Bruno Martin Gachon, Howard Riezman, Benjamin Dieter Weger

Circadian clocks play an important role in lipid homeostasis, with impact on various metabolic diseases. Due to the central role of skeletal muscle in whole-body metabolism, we aimed at studying muscle lipid profiles in a temporal manner. Moreover, it has ...

Natl Acad Sciences2017

Muscle Activation Variability Is Inversely Correlated with Walking Speed

Auke Ijspeert, Florin Dzeladini, Amy Roning Wu, Cole Stewart Simpson, Amandine Grappe

Individuals withmotor impairments typically walk at much slower speeds than their unimpaired counterparts, yet their gait data is still evaluated against the relatively faster gait of healthy subjects. Therefore a good understanding of unimpaired gait at e ...

Springer International Publishing Ag2017

Dispositif et procédé pour l'évaluation de la contraction cellulaire

Boris Hinz, Pierre Jean Arnould Wipff

A method for assessing cell contraction includes adhering contractile cells to an oxidized and cellular adhesion activated surface of a biocompatible silicone elastomer film. The biocompatible silicone elastomer film allows the cells to contract and wrinkl ...

2017

Multi-harmonic imaging in the second near-infrared window of nanoparticle-labeled stem cells as effective monitoring tool in tissue depth

Sandrine Gerber, Solène Marcelle Françoise Marie Passemard, Luigi Bonacina

In order to assess the therapeutic potential of cell-based strategies, it is of paramount importance to elaborate and validate new tools for monitoring the behavior of injected cells in terms of tissue dissemination and engraftment properties. Here, we app ...

American Chemical Society2017

Predicting Partitioning and Diffusion Properties of Nonpolar Chemicals in Biotic Media and Passive Sampler Phases by GC x GC

Jeremy Samuel Arey, Deedar Nabi

The chemical parameters needed to explain and predict bioavailability, biodynamics, and baseline toxicity are not readily available for most nonpolar chemicals detected in the environment. Here, we demonstrate that comprehensive two-dimensional gas chromat ...

Amer Chemical Soc2017

PPAR delta Promotes Running Endurance by Preserving Glucose

Johan Auwerx, Hao Li, Vincenzo Sorrentino

Management of energy stores is critical during endurance exercise; a shift in substrate utilization from glucose toward fat is a hallmark of trained muscle. Here we show that this key metabolic adaptation is both dependent on muscle PPAR delta and stimulat ...

Cell Press2017

Combining Electromyography and Tactile Myography to Improve Hand and Wrist Activity Detection in Prostheses

Sylvain Calinon, Noémie Laure Gwendoline Jaquier

Despite recent advances in prosthetics and assistive robotics in general, robust simultaneous and proportional control of dexterous prosthetic devices remains an unsolved problem, mainly because of inadequate sensorization. In this paper, we study the appl ...

2017

Integrated Heart-Coupling multiscale and multiphysics models for the simulation of the cardiac function

Alfio Quarteroni, Ricardo Esteban Ruiz Baier, Toni Mikael Lassila, Simone Rossi

Mathematical modeling of the human heart and its function can expand our understanding of various cardiac diseases, which remain the most common cause of death in the developed world. Like other physiological systems, the heart can be understood as a compl ...

Elsevier Science Sa2017

An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondria! metabolism

Johan Auwerx, Pénélope Andreux, Xu Wang

Objective: Strategies improving skeletal muscle mitochondrial capacity are commonly paralleled by improvements in (metabolic) health. We and others previously identified microRNAs regulating mitochondrial oxidative capacity, but data in skeletal muscle are ...

Elsevier Science Bv2017

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