Publications related to Bundle of His

In Vitro Cytocompatibility Assessment of Ti-Modified, Silicon-oxycarbide-Based, Polymer-Derived, Ceramic-Implantable Electrodes under Pacing Conditions

Jürgen Brugger, Demetri Psaltis, Giulia Panusa, Pierrick Guy Robert Clément, Eirini Kakkava, Jongmoon Jang

Polymer-derived ceramics (PDC) have recently gained increased interest in the field of bioceramics. Among PDC's, carbon-rich silicon oxycarbide ceramics (SiOC) possess good combined electrical and mechanical properties. Their durability in aggressive envir ...

AMER CHEMICAL SOC2020

High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue

Herbert Shea, Matthias Imboden, Samuel Rosset, Alexandre Poulin, Christian Dellenbach, Stephan Rohr, Etienne de Coulon

Systematic investigations of the effects of mechano-electric coupling (MEC) on cellular cardiac electrophysiology lack experimental systems suitable to subject tissues to in-vivo like strain patterns while simultaneously reporting changes in electrical act ...

2019

Intracellular Recording of Cardiomyocyte Action Potentials with Nanopatterned Volcano-Shaped Microelectrode Arrays

Philippe Renaud, Arnaud Bertsch, Benoît Xavier Emmanuel Desbiolles

Micronanotechnology-based multielectrode ar- rays have led to remarkable progress in the field of transmembrane voltage recording of excitable cells. However, providing long-term optoporation- or electroporation-free intracellular access remains a consider ...

2019

Improved hybrid/GPU algorithm for solving cardiac electrophysiology problems on Purkinje networks

Alfio Quarteroni, Christian Vergara, Toni Mikael Lassila

Cardiac Purkinje fibers provide an important pathway to the coordinated contraction of the heart. We present a numerical algorithm for the solution of electrophysiology problems across the Purkinje network that is efficient enough to be used in in silico s ...

Wiley2017

A coupled 3D-1D numerical monodomain solver for cardiac electrical activation in the myocardium with detailed Purkinje network

Alfio Quarteroni, Christian Vergara, Toni Mikael Lassila

We present a model for the electrophysiology in the heart to handle the electrical propagation through the Purkinje system and in the myocardium, with two-way coupling at the Purkinje-muscle junctions. In both the subproblems the monodomain model is consid ...

Elsevier2016

MATHICSE Technical Report : Improved hybrid/GPU algorithm for solving cardiac electro-physiology problems on Purkinje networks

Alfio Quarteroni, Christian Vergara, Toni Mikael Lassila

The cardiac Purkinje fibres provide an important stimulus to the coordinated contraction of the heart. We present a numerical algorithm for the solution of electrophysiology problems on the Purkinje network that is efficient enough to be used on realistic ...

MATHICSE2016

An effective algorithm for the generation of patient-specific Purkinje networks in computational electrocardiology

Fabio Nobile, Christian Vergara, Elena Faggiano

The Purkinje network is responsible for the fast and coordinated distribution of the electrical impulse in the ventricle that triggers its contraction. Therefore, it is necessary to model its presence to obtain an accurate patient-specific model of the ven ...

Elsevier2015

Patient-specific generation of the Purkinje network driven by clinical measurements of a normal propagation

Alfio Quarteroni, Fabio Nobile, Christian Vergara, Elena Faggiano

The propagation of the electrical signal in the Purkinje network is the starting point for the activation of the ventricular muscular cells leading to the contraction of the ventricle. In the computational models, describing the electrical activity of the ...

Springer Verlag2014

Computational generation of the Purkinje network driven by clinical measurements: The case of pathological propagations

Alfio Quarteroni, Fabio Nobile, Christian Vergara, Elena Faggiano

To properly describe the electrical activity of the left ventricle, it is necessary to model the Purkinje fibers, responsible for the fast and coordinate ventricular activation, and their interaction with the muscular propagation. The aim of this work is t ...

2014

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