Concept

Harmonic mean p-value

Related publications (19)

Multiple testing with test statistics following heavy-tailed distributions

In multiple testing problems where the components come from a mixture model of noise and true effect, we seek to first test for the existence of the non-zero components, and then identify the true alternatives under a fixed significance level

\alpha

. Two ...

EPFL2021

High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis

Theo Lasser

Fluorescent nanodiamonds (fNDs) represent an emerging class of nanomaterials offering great opportunities for ultrahigh resolution imaging, sensing and drug delivery applications. Their biocompatibility, exceptional chemical and consistent photostability r ...

AMER CHEMICAL SOC2019

Bayesian association scan reveals loci associated with human lifespan and linked biomarkers

Johan Auwerx, Bart Deplancke, Murielle Bochud, Hao Li, Vincenzo Sorrentino, Maria Litovchenko, Roel Paulus Josephus Bevers, Sina Rüeger, Andrea Komljenovic

The enormous variation in human lifespan is in part due to a myriad of sequence variants, only a few of which have been revealed to date. Since many life-shortening events are related to diseases, we developed a Mendelian randomization-based method combini ...

Nature Publishing Group2017

Multiple comparisons procedures for complex dependent data with application to study human brain complex network properties

Djalel Eddine Meskaldji

We consider the problem of testing positively dependent multiple hypotheses, assuming that prior information about the dependence structure is available. We propose two-step multiple comparisons procedures that exploit the prior information of the dependen ...

2015

The control of the scaled false discovery rate, a flexible and comprehensive error control and a powerful theoretical tool in multiple testing

Dimitri Nestor Alice Van De Ville, Stephan Morgenthaler, Djalel Eddine Meskaldji

Given the large number of papers written over the last ten years on error controls in high dimensional multiple testing, it would be worthwhile to consider a single comprehensive technique that allows user flexibility in error control when dealing with big ...

2015

Graph Embedded Nonparametric Mutual Information For Supervised Dimensionality Reduction

Nikolaos Arvanitopoulos Darginis

In this paper, we propose a novel algorithm for dimensionality reduction that uses as a criterion the mutual information (MI) between the transformed data and their cor- responding class labels. The MI is a powerful criterion that can be used as a proxy to ...

Institute of Electrical and Electronics Engineers2015

Improved methodology and set-point design for diagnosis of model-plant mismatch in control loops using plant-model ratio

Alireza Karimi

Performance of any model-based control scheme depends on the quality of model. When these schemes deliver poor loop performance due to model-plant mismatch (MPM), a detection of the same needs to be in place. A recently introduced plant model ratio (PMR) n ...

Elsevier2014

Fourier Analysis of Functional Time Series, with Applications to DNA Dynamics

Shahin Tavakoli

This work is about time series of functional data (functional time series), and consists of three main parts. In the first part (Chapter 2), we develop a doubly spectral decomposition for functional time series that generalizes the Karhunen–Loève expansion ...

EPFL2014

Two step multiple comparisons procedures for positively dependent data with application to detecting differences in human brain network topologies

Jean-Philippe Thiran, Stephan Morgenthaler, Patric Hagmann, Djalel Eddine Meskaldji

We consider the problem of testing positively dependent multiple hypotheses assuming that a prior information about the dependence structure is available. We propose two-step multiple comparisons procedures that exploit the prior information of the depende ...

Arxiv2013

Critical issues in using the common mixture toxicity models concentration addition or response addition on species sensitivity distributions: A theoretical approach

Vincent Gregorio

The risk of chemical mixtures to ecosystems is often assessed by applying the model of concentration addition or response addition combined with species sensitivity distribution (SSD) curves. Mixture effect predictions have been shown to be consistent only ...

Society of Environmental Toxicology and Chemistry Press2013

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Multiple testing with test statistics following heavy-tailed distributions

Zhiwen Jiang

\alpha

. Two ...

EPFL2021