Publications related to Aminoglycoside

Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform

Sandor Kasas, Anthony Vocat, Gino Cathomen, Eric Delarze, Florian Tagini, Laura Munch

Antimicrobial resistance (AMR) is a major public health threat, reducing treatment options for infected patients. AMR is promoted by a lack of access to rapid antibiotic susceptibility tests (ASTs). Accelerated ASTs can identify effective antibiotics for t ...

Nature Portfolio2024

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Camille Véronique Bernadette Goemans, Christian Eugen Zimmerli, Martin Beck

Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative b ...

2024

Nanomotion Detection-Based Rapid Antibiotic Susceptibility Testing

Sandor Kasas, María Inés Villalba, Anton Malovichko

Rapid antibiotic susceptibility testing (AST) could play a major role in fighting multidrug-resistant bacteria. Recently, it was discovered that all living organisms oscillate in the range of nanometers and that these oscillations, referred to as nanomoti ...

2021

Neonatal Manifestations of Chronic Granulomatous Disease: MAS/HLH and Necrotizing Pneumonia as Unusual Phenotypes and Review of the Literature

Alessandro Borghesi

Chronic granulomatous disease (CGD) is a rare inborn error of immunity (IEI), characterized by a deficient phagocyte killing due to the inability of NADPH oxidase to produce reactive oxygen species in the phagosome. Patients with CGD suffer from severe and ...

SPRINGER/PLENUM PUBLISHERS2021

Soft-probe-scanning electrochemical microscopy reveals electrochemical surface reactivity of E. coli biofilms

Hubert Girault, Emad Oveisi, Horst Pick, Andreas Stephan Lesch, Sorour Darvishi

Investigating and understanding dynamic biofilm growth mechanisms is challenging, often because state-of-theart optical characterization tools provide limited information. Micrometric electrochemical imaging of Escherichia coli biofilms using Soft-Probe-Sc ...

2021

Soft-probe-scanning electrochemical microscopy reveals electrochemical surface reactivity of E. coli biofilms

Hubert Girault, Emad Oveisi, Horst Pick, Andreas Stephan Lesch, Sorour Darvishi

Investigating and understanding dynamic biofilm growth mechanisms is challenging, often because state-of-the-art optical characterization tools provide limited information. Micrometric electrochemical imaging of Escherichia coli biofilms using Soft-Probe-S ...

2021

Unravelling the collateral damage of antibiotics on gut bacteria

Camille Véronique Bernadette Goemans

Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the composition of gut microbiota and causing dysbiosis and disease1. Despite this well-known collateral damage, the activity spectrum of different antibiotic classes on ...

2021

A Rapid Unraveling of the Activity and Antibiotic Susceptibility of Mycobacteria

Giovanni Dietler, Sandor Kasas, Giovanni Longo, Leonardo Venturelli

The development of antibiotic-resistant bacteria is a worldwide health-related emergency that calls for new tools to study the bacterial metabolism and to obtain fast diagnoses. Indeed, the conventional analysis time scale is too long and affects our abili ...

AMER SOC MICROBIOLOGY2019

Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma

Stewart Cole, Anthony Vocat, Thierry Buclin, Jeff Pitteloud

The emergence of Mycobacterium tuberculosis strains resistant to current first-line antibiotic regimens constitutes a major global health threat. New treatments against multidrug-resistant tuberculosis (MDR-TB) are thus eagerly needed in particular in coun ...

PUBLIC LIBRARY SCIENCE2019

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Aminoglycoside

Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Nanomotion Detection-Based Rapid Antibiotic Susceptibility Testing

Neonatal Manifestations of Chronic Granulomatous Disease: MAS/HLH and Necrotizing Pneumonia as Unusual Phenotypes and Review of the Literature

Soft-probe-scanning electrochemical microscopy reveals electrochemical surface reactivity of E. coli biofilms

Soft-probe-scanning electrochemical microscopy reveals electrochemical surface reactivity of E. coli biofilms

Unravelling the collateral damage of antibiotics on gut bacteria

A Rapid Unraveling of the Activity and Antibiotic Susceptibility of Mycobacteria

Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma

More Medicines for Tuberculosis: Fuelling Drug Discovery against Mycobacterium tuberculosis

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Chat with Graph Search

Neonatal Manifestations of Chronic Granulomatous Disease: MAS/HLH and Necrotizing Pneumonia as Unusual Phenotypes and Review of the Literature

Soft-probe-scanning electrochemical microscopy reveals electrochemical surface reactivity of E. coli biofilms

More Medicines for Tuberculosis: Fuelling Drug Discovery against Mycobacterium tuberculosis

Nanomotion Detection-Based Rapid Antibiotic Susceptibility Testing

Unravelling the collateral damage of antibiotics on gut bacteria

A Rapid Unraveling of the Activity and Antibiotic Susceptibility of Mycobacteria

Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma

Soft-probe-scanning electrochemical microscopy reveals electrochemical surface reactivity of E. coli biofilms

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction