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Cells consume extra-cellular nutrients and resources to maintain cellular fitness. Extra-cellular conditions vary over time. Cellular programs encoded in genes adjust to adapt to the environments. Gene regulatory networks (GRNs) have evolved to be responsi ...
Compared to estrogen receptor-negative (ER-) breast cancer (BC), ER+ BC often manifests with a latent disease that recurs decades after initial diagnosis. The mechanisms governing dormancy and distant recurrence of ER+ tumors remain elusive due to the lack ...
Laser surface remelting at various velocities has been employed to study the selection of microstructures of high-purity Fe-C-Si alloys containing nominally 3.2 to 4.2 wt.% C and 1 to 3 wt.% Si. The microstructure of the remelted region consisted of metast ...
WALTER DE GRUYTER GMBH2021
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Acinetobacter baumannii is a severe threat to human health as a frequently multidrug-resistant hospital-acquired pathogen. Part of the danger from this bacterium comes from its genome plasticity and ability to evolve quickly by taking up and recombining ex ...
Follicular lymphoma (FL) is an incurable form of B-cell lymphoma. Genomic alterations that inactivate RB signaling are surprisingly common in indolent FL. We show that FLs that are positive for phosphorylated RB respond to dual CDK4/BCL2 inhibition. Our re ...
Active phase loss mechanisms from Ru/AC catalysts were studied in continuous supercritical water gasification (SCWG) for the first time by analysing the Ru content in process water with low limit-of-detection time-resolved ICP-MS. Ru loss was investigated ...
Active phase loss mechanisms from Ru/AC catalysts were studied in continuous supercritical water gasification (SCWG) for the first time by analysing the Ru content in process water with low limit-of-detection time-resolved ICP-MS. Ru loss was investigated ...
Purpose: To report multimodal imaging findings including optical coherence tomography angiography (OCT-A) of a patient presenting with a quiescent choroidal neovascularization (CNV) in one eye and an active CNV in the fellow eye, complicating retinitis pig ...
Liquid-liquid phase separation (LLPS) of proteins and RNAs has emerged as the driving force underlying the formation of membrane-less organelles. Such biomolecular condensates have various biological functions and have been linked to disease. The protein F ...
Intracellular density impacts the physical nature of the cytoplasm and can globally affect cellular processes, yet density regulation remains poorly understood. Here, using a new quantitative phase imaging method, we determined that dry-mass density in fis ...
