Concept

G0 phase

Related publications (142)

The Periostin/Integrin-alpha v Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver

We earlier showed that outside-in integrin signaling through POSTN-ITGAV interaction plays an important role in regulating adult he-matopoietic stem cell (HSC) quiescence. Here, we show that Itgav deletion results in increased frequency of phenotypic HSCs ...

2020

Notch Signaling - a Booster of Chronic Lymphocytic Leukemia During Initiation and Disease Progression

Delphine Maude Tardivon

Chronic lymphocytic leukemia (CLL) is a B cell malignancy and represents the most common leukemia in adults within the Western world. This disease mainly affects the elderly, with a median age of diagnosis over 70. The disease course is highly variable amo ...

EPFL2020

Incommensurate crystal structure of PbHfO3

Alla Arakcheeva

Controversy in the description/identification of so-called intermediate phase(s) in PbHfO3, stable in the range similar to 420-480 K, has existed for a few decades. A synchrotron diffraction experiment on a partially detwinned crystal allowed the structure ...

INT UNION CRYSTALLOGRAPHY2020

Deformation and degradation of superelastic NiTi under multiaxial loading

Helena Van Swygenhoven, Steven Van Petegem, Efthymios Polatidis, Nicola Casati, Wei-Neng Hsu

The degradation of the superelastic properties of a commercial NiTi alloy is studied during uniaxial, biaxial and load-path-change cycling performed in-situ with synchrotron X-ray diffraction. Careful examination of the diffraction pattern during uniaxial ...

PERGAMON-ELSEVIER SCIENCE LTD2019

Dynamics of protein synthesis and degradation through the cell cycle

David Michael Suter, Andrea Brigitta Alber

Protein expression levels depend on the balance between their synthesis and degradation rates. Even quiescent (G(0)) cells display a continuous turnover of proteins, despite protein levels remaining largely constant over time. In cycling cells, global prot ...

TAYLOR & FRANCIS INC2019

Phase transitions in AuCu alloy are investigated using in situ temperature XRD and mechanical spectroscopy. The measurements are carried out from room temperature up to 973 K starting from the ordered phase AuCuI. Using a temperature ramp rate of 1 K/min, ...

ELSEVIER SCIENCE SA2019

The role of OCT4 and SOX2 in regulating chromatin accessibility and cell fate across the cell cycle in embryonic stem cells

Torgil Elias Friman

Precise spatiotemporal regulation of gene expression is essential for development and homeostasis of complex organisms. This is achieved in large part by sequence-specific transcription factors (TF) that bind to genomic regulatory elements to activate or r ...

EPFL2019

Bacterial cell cycle dynamics: size regulation during exponential growth and role of polyphosphate during starvation response

Aster Louis K Vanhecke

Bacteria are the most diverse and abundant kingdom of life and have adapted to survive and thrive in habitats around the globe. When provided with ample nutrients they grow and divide at staggering rates, increasing their population exponentially. Upon nut ...

EPFL2019

Distinct Contributions of Whisker Sensory Cortex and Tongue-Jaw Motor Cortex in a Goal-Directed Sensorimotor Transformation

Carl Petersen, Georgios Foustoukos, Matthieu Pierre Auffret, Sami El-Boustani, Johannes Maria Mayrhofer, Keita Tamura

The neural circuits underlying goal-directed sensorimotor transformations in the mammalian brain are incompletely understood. Here, we compared the role of primary tongue-jaw motor cortex (tjM1) and primary whisker sensory cortex (wS1) in head-restrained m ...

CELL PRESS2019

Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone

Freddy Radtke

Neurogenesis continues in the ventricular-subventricular zone (V-SVZ) of the adult forebrain from quiescent neural stem cells (NSCs). V-SVZ NSCs are a reservoir for new olfactory bulb (OB) neurons that migrate through the rostral migratory stream (RMS). To ...

2018

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