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Caenorhabditis elegans is one of the most attractive model organisms in biomedical research for understanding human diseases and for drug testing at a whole-organism level, since many biological pathways and genes have been conserved between itself and hum ...
The anaerobic threshold (AT) is a good index of personal endurance but needs a laboratory setting to be determined. It is important to develop easy AT field measurements techniques in order to rapidly adapt training programs. In the present study, it is po ...
2015
Available data are limited concerning long-term lung function (LF) evolution after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in lung transplant (LT) recipients. The aim of this study is to determine the effect of first SARS-CoV ...
WILEY2023
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Objectives Parametric response mapping (PRM) enables the evaluation of small airway disease (SAD) at the voxel level, but requires both inspiratory and expiratory chest CT scans. We hypothesize that deep learning PRM from inspiratory chest CT scans can eff ...
London2023
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Despite the huge expansion in recent years of sweat sensing and wearable technologies, several challenges are still open, including poor sample collection, separate sampling and analysis, low multi-sensing capabilities and materials toxicity. In this work, ...
2020
Main project. Chronic episodes of sudden pulmonary deterioration followed by insufficient recoveries from antibiotic treatments are the main driver of morbidity and mortality in Cystic Fibrosis (CF). Study of recovery is performed to improve CF care monito ...
2021
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Mitochondrial fusion and fission events, collectively known as mitochondrial dynamics, act as quality control mechanisms to ensure mitochondrial function and fine-tune cellular bioenergetics. Defective mitofusin 2 (Mfn2) expression and enhanced mitochondri ...
The aim of this study is to investigate the temperature boundary layer around a human body in a quiescent indoor environment. The air temperature, mean in time and standard deviation of the temperature fluctuations around a breathing thermal manikin are ex ...
The product of resistance, R, and compliance, C (RC time), of the entire pulmonary circulation is constant. It is unknown if this constancy holds for individual lungs. We determined R and C in individual lungs in chronic thromboembolic pulmonary hypertensi ...
AREG-/- mice demonstrate impaired mammary development and form only rudimentary ductal epithelial trees, however, AREG-/- glands are still capable of undergoing alveologenesis and lactogenesis during pregnancy. Transplantation of AREG-/- mammary epithelial ...
