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Explores the applications of CRISPR-Cas in genome editing, focusing on engineering bacterial genomes, curing genetic diseases, guide RNA simplicity, Cas9 specificity, DNA damage mechanisms, and base editing.
Explores early embryogenesis, ES cell differentiation, disease modeling, neuronal function, genome editing, 'minibrains', in vitro retina and intestine, single-cell analysis, and lineage tracing.
