Concept

Schizotypy

Related publications (35)

20-years work investigating the shine-through paradigm in the schizophrenia spectrum: what is next?

Michael Herzog, Simona Adele Garobbio, Maya Roinishvili

In the past 20 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...

2023

Amygdala subdivisions exhibit aberrant whole-brain functional connectivity in relation to stress intolerance and psychotic symptoms in 22q11.2DS

Dimitri Nestor Alice Van De Ville, Farnaz Delavari, Halima Rafi

The amygdala is a key region in emotional regulation, which is often impaired in psychosis. However, it is unclear if amygdala dysfunction directly contributes to psychosis, or whether it contributes to psychosis through symptoms of emotional dysregulation ...

SPRINGERNATURE2023

Developmental Trajectories of Cortical Thickness in Relation to Schizotypy During Adolescence

Marie Schaer

Investigating potential gray matter differences in adolescents presenting higher levels of schizotypy personality traits could bring further insights into the development of schizophrenia spectrum disorders. Research has yet to examine the morphological co ...

2020

Identifying neurodevelopmental anomalies of white matter microstructure associated with high risk for psychosis in 22q11.2DS

Maude Schneider, Marie Schaer, Daniela Maria Zöller, Maria Carmela Padula

Disruptions of white matter microstructure have been widely reported in schizophrenia. However, the emergence of these alterations during preclinical stages remains poorly understood. 22q11.2 Deletion Syndrome (22q11.2DS) represents a unique model to study ...

SPRINGERNATURE2020

Visual masking in Schizophrenia: an endophenotype and its neural correlates

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod

Objective: In visual backward masking, a target is followed by a mask, which deteriorates performance on the target. Masking is a very sensitive endophenotype for schizophrenia. Patients and their siblings (to a lesser extent) show strong performance defic ...

2019

Electrophysiological correlates of visual backward masking in the schizophrenia continuum

Ophélie Gladys Favrod

In visual backward masking (VBM), a target is followed by a mask. Over the past decade, a VBM task, called the Shine-Through paradigm (ST), has been shown to be a very sensitive endophenotype of schizophrenia. In the present thesis, the electrophysiologica ...

EPFL2019

EEG microstates and the schizophrenia spectrum: evidence for compensation mechanisms

Michael Herzog, Christine Mohr, Maya Roinishvili, Ophélie Gladys Favrod, Patricia Figueiredo

Introduction: Electroencephalogram (EEG) microstates are on-going scalp potential configurations that remain stable for around 80 ms (1). Four recurrent and dominant classes of microstates (labeled A-D) are observed in resting-state EEG, explaining around ...

2019

EEG microstates in schizophrenia: a candidate endophenotype

Michael Herzog, Christine Mohr, Maya Roinishvili, Ophélie Gladys Favrod, Patricia Figueiredo

Objective: Electroencephalogram (EEG) microstates are on-going scalp potential configurations that remain stable for around 80 ms. Abnormal temporal dynamics of specific classes of microstates have been suggested as a potential endophenotype for schizophre ...

2019

(Visual) Endophenotypes in schizophrenia research

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Albulena Jashari-Shaqiri

Objective: Schizophrenia is a heterogeneous disease strongly influenced by genetic disposition. However, genetic studies have shown that each single nucleotide polymorphism (SNP) contributes very little to the disease. For this reason, endophenotypes, loca ...

2019

Dynamic organization of human brain function and its relevance for psychosis vulnerability

Daniela Maria Zöller

The brain is the substrate of a complex dynamic system providing a remarkably varied range of functionalities, going from simple perception to higher-level cognition. Disturbances in its complex dynamics can cause an equally vast variety of mental disorder ...

EPFL2019

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.