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Precise information about kinetic properties of enzymes within a biochemical network is a necessary ingredient of any successful metabolic engineering design. Such information inevitably involves uncertainty due to changes in cellular and process parameter ...
Engineering of large-scale metabolic pathways to maximize production of a certain substance or to minimize creation of undesired chemicals require explicit information about the underlying enzyme kinetics. Unfortunately, such information is frequently not ...
We re-analyse earlier measurements of resistance R and piezoresistance K in RuO2-based thick-film resistors (TFRs). The percolating nature of transport in these systems is well accounted by values of the transport exponent t larger than its universal value ...
Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor, which controls adipocyte differentiation. We targeted with homologous recombination the PPAR gamma 2-specific exon B, resulting in a white adipose tissue knockdown of PPAR ...
It is widely accepted that metabolic rates scale across species approximately as the 3/4 power of mass in most if not all groups of organisms. Metabolic demand per unit mass thus decreases as body mass increases. Metabolic rates reflect both the ability of ...
[1] We derive a new allometric scaling law for loopless networks, which we confirm with studies on rivers, exact network results and computer simulations. We provide evidence suggesting that ensemble averaging of the allometric property (where individual r ...
An analysis of the effect of magnetic geometry on heat flux in a wide range of single null diverted discharge configurations with 1.5 < κ(95) < 2.2, 0.2 < δ(95) < 0.45 suggests that elongation is beneficial for confinement. If heat diffusivitie ...
To evaluate the contribution of genetic background to phenotypic variation, we compared a large range of biochemical and metabolic parameters at different ages of four inbred mice strains, C57BL/6J, 129SvPas, C3HeB/FeJ, and Balb/cByJ. Our results demonstra ...
We investigate the tunneling-percolation mechanism of DC transport nonuniversality for conducting particles of diameter Φ placed in series within the bonds of length Lof a regular lattice model. When L/Φ→∞ the resulting bond conductance distribution functi ...
We show that in RuO2–glass composites the nonuniversal resistivity exponent can be modulated by an applied mechanical strain, signaled by a logarithmic divergence of the piezoresistive response at the percolation threshold. We interpret this phenomenon as ...
