Infant respiratory distress syndromeInfantile respiratory distress syndrome (IRDS), also called respiratory distress syndrome of newborn, or increasingly surfactant deficiency disorder (SDD), and previously called hyaline membrane disease (HMD), is a syndrome in premature infants caused by developmental insufficiency of pulmonary surfactant production and structural immaturity in the lungs. It can also be a consequence of neonatal infection and can result from a genetic problem with the production of surfactant-associated proteins.
Obligate nasal breathingObligate nasal breathing describes a physiological necessity to breathe through the nose (or other forms of external nasal passages, depending on the species) as opposed to breathing through the mouth. The term may be misleading, as it implies that the organism has no choice but to breathe through its nose; however, it is also used to describe cases where effective breathing through the mouth is possible but not preferred. Alternatively, the term has been defined by some as the ability to breathe through the nose while swallowing.
Lung budThe lung bud sometimes referred to as the respiratory bud forms from the respiratory diverticulum, an embryological endodermal structure that develops into the respiratory tract organs such as the larynx, trachea, bronchi and lungs. It arises from part of the laryngotracheal tube. In the fourth week of development, the respiratory diverticulum, starts to grow from the ventral (front) side of the foregut into the mesoderm that surrounds it, forming the lung bud.
Lamella (surface anatomy)In surface anatomy, a lamella is a thin plate-like structure, often one amongst many lamellae very close to one another, with open space between. Aside from respiratory organs, they appear in other biological roles including filter feeding and the traction surfaces of geckos. In fish, gill lamellae are used to increase the surface area in contact with the environment to maximize gas exchange (both to attain oxygen and to expel carbon dioxide) between the water and the blood.
HyperpneaHyperpnea, or hyperpnoea (forced respiration), is increased volume of air taken during breathing. It can occur with or without an increase in respiration rate. It is characterized by deep breathing. It may be physiologic—as when required by oxygen to meet metabolic demand of body tissues (for example, during or after heavy exercise, or when the body lacks oxygen at high altitude or as a result of anemia, or any other condition requiring more respiration)—or it may be pathologic, as when sepsis is severe or during pulmonary edema.
Hypoxic pulmonary vasoconstrictionHypoxic pulmonary vasoconstriction (HPV), also known as the Euler-Liljestrand mechanism, is a physiological phenomenon in which small pulmonary arteries constrict in the presence of alveolar hypoxia (low oxygen levels). By redirecting blood flow from poorly-ventilated lung regions to well-ventilated lung regions, HPV is thought to be the primary mechanism underlying ventilation/perfusion matching. The process might initially seem counterintuitive, as low oxygen levels might theoretically stimulate increased blood flow to the lungs to increase gas exchange.
MesotheliomaMesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs (known as the mesothelium). The area most commonly affected is the lining of the lungs and chest wall. Less commonly the lining of the abdomen and rarely the sac surrounding the heart, or the sac surrounding the testis may be affected. Signs and symptoms of mesothelioma may include shortness of breath due to fluid around the lung, a swollen abdomen, chest wall pain, cough, feeling tired, and weight loss.
Modes of mechanical ventilationModes of mechanical ventilation are one of the most important aspects of the usage of mechanical ventilation. The mode refers to the method of inspiratory support. In general, mode selection is based on clinician familiarity and institutional preferences, since there is a paucity of evidence indicating that the mode affects clinical outcome. The most frequently used forms of volume-limited mechanical ventilation are intermittent mandatory ventilation (IMV) and continuous mandatory ventilation (CMV).
Serous fluidIn physiology, serous fluid or serosal fluid (originating from the Medieval Latin word serosus, from Latin serum) is any of various body fluids resembling serum, that are typically pale yellow or transparent and of a benign nature. The fluid fills the inside of body cavities. Serous fluid originates from serous glands, with secretions enriched with proteins and water. Serous fluid may also originate from mixed glands, which contain both mucous and serous cells.
SpirometerA spirometer is an apparatus for measuring the volume of air inspired and expired by the lungs. A spirometer measures ventilation, the movement of air into and out of the lungs. The spirogram will identify two different types of abnormal ventilation patterns, obstructive and restrictive. There are various types of spirometers that use a number of different methods for measurement (pressure transducers, ultrasonic, water gauge). Pulmonary function testing A spirometer is the main piece of equipment used for basic Pulmonary Function Tests (PFTs).
