Concept

Blood cell

Related publications (246)

Response characteristics of arsenic-sensitive bioreporters expressing the gfp reporter gene

This paper describes the development of an analytical technique for arsenic analyses that is based on genetically-modified bioreporter bacteria bearing a gene encoding for the production of a green fluorescent protein (gfp). Upon exposure to arsenic (in th ...

2005

Embryonic stem cell-derived hematopoietic stem cells

Olaia Maria Naveiras Torres-Quiroga

Despite two decades of studies documenting the in vitro blood-forming potential of murine embryonic stem cells (ESCs), achieving stable long-term blood engraftment of ESC-derived hematopoietic stem cells in irradiated mice has proven difficult. We have exp ...

National Academy of Sciences2005

Tandem cell for water cleavage by visible light

Michael Graetzel

A tandem cell or photoelectrochemical system for the cleavage of water to hydrogen and oxygen by visible light has two superimposed photocells, both cells being connected electrically. The photoactive material in the top cell is a semiconducting oxide plac ...

2005

Paradigms of notch signaling in mammals

Freddy Radtke, Anne Wilson

Notch proteins regulate a broad spectrum of cell fate decisions and differentiation processes during fetal and postnatal life. These proteins are involved in organogenesis during embryonic development as well as in the maintenance of homeostasis of self-re ...

2005

More than just proliferation: Myc function in stem cells

Anne Wilson

Adult stem cells are essential to maintain regenerative tissues such as skin epidermis, gastrointestinal mucosa or the hematopoietic system. Recent studies in mice suggest that the transcription factor and oncoprotein c-Myc has unexpected functions during ...

2005

Functionalized pyrrolidines as alpha-mannosidase inhibitors and growth inhibitors of human glioblastoma and melanoma cells

Pierre Vogel, Sandrine Gerber, Sylvain Favre, Hélène Fiaux

New substituted pyrrolidine-3,4-diol derivatives were prepared from D-(-)- and L-(+)-phenyl glycinol. The influence of the configuration and the substitution of the lateral side chain of these derivatives on the inhibition of 25 commercial glycosidases wer ...

2005

Overexpression of VEGF-C causes transient lymphatic hyperplasia but not increased lymphangiogenesis in regenerating skin

Melody Swartz

Vascular endothelial growth factor (VEGF)-C is necessary for lymphangiogenesis and holds potential for lymphangiogenic therapy in diseases lacking adequate lymphatic drainage. However, the ability of VEGF-C to enhance sustainable, functional lymphatic grow ...

2005

Synchrotron refractive-index microradiography of human liver cancer tissue

Yiming Li, Giorgio Margaritondo

Three human liver tissue samples (similar to 5 mm x 40 mm x 20 mm) were excised from a cancer patient's liver during surgery. The microradiology analysis was performed with a non-standard approach on a synchrotron. High-resolution refractive-index edge-enh ...

2005

Dielectric spectroscopy in a microfabricated flow cytometer

Shady Didier Gawad

In this thesis, a new microfabricated flow cytometer for single cell discrimination based on dielectric spectroscopy is presented. Integrated tools for rapid in-flow cell handling are also demonstrated. Signal amplification and analysis as well as the chip ...

EPFL2004

Interstitial flow differentially stimulates blood and lymphatic endothelial cell morphogenesis in vitro

Melody Swartz

Whereas high shearing flows are known to induce endothelial cell remodeling, we show here that very low interstitial flow rates trigger endothelial cell morphogenesis in 3D cultures. Interstitial flow is a functionally critical component of the circulation ...

2004

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