Publications related to Duct (anatomy)

Membrane expression of the estrogen receptor ER alpha is required for intercellular communications in the mammary epithelium

Cathrin Brisken, Stéphanie Cagnet

17 beta-Estradiol induces the postnatal development of mammary gland and influences breast carcinogenesis by binding to the estrogen receptor ER alpha. ER alpha acts as a transcription factor but also elicits rapid signaling through a fraction of ER alpha ...

COMPANY BIOLOGISTS LTD2020

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

Cathrin Brisken, Giovanna Ambrosini, Marian Caikovski, Philipp Bucher, Renuga Devi Rajaram, Patrik Aouad, Dalya Ataca, Marie Shamseddin, Céline Berthe Constantin, Csaba Ferenc László

Estrogens and progesterone control breast development and carcinogenesis via their cognate receptors expressed in a subset of luminal cells in the mammary epithelium. How they control the extracellular matrix, important to breast physiology and tumorigenes ...

2020

Oestrogen receptor alpha AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium

Cathrin Brisken, Georgios Sflomos, Ayyakkannu Ayyanan, Valentina Scabia, Patrik Aouad, Dalya Ataca, Stéphanie Cagnet

Oestrogen receptor alpha (ER alpha) is a transcription factor with ligand-independent and ligand-dependent activation functions (AF)-1 and -2. Oestrogens control postnatal mammary gland development acting on a subset of mammary epithelial cells (MECs), ter ...

NATURE PUBLISHING GROUP2018

Progesterone and Overlooked Endocrine Pathways in Breast Cancer Pathogenesis

Cathrin Brisken, Kathryn Hess Bellwald

Worldwide, breast cancer incidence has been increasing for decades. Exposure to reproductive hormones, as occurs with recurrent menstrual cycles, affects breast cancer risk, and can promote disease progression. Exogenous hormones and endocrine disruptors h ...

2015

Cell Cycle-Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas

Anne Grapin-Botton, Laurence Anne E Lemaire, Yung Hae Kim

Organogenesis relies on the spatiotemporal balancing of differentiation and proliferation driven by an expanding pool of progenitor cells. In the mouse pancreas, lineage tracing at the population level has shown that the expanding pancreas progenitors can ...

Public Library Science2015

Endocrine hormones and local signals during the development of the mouse mammary gland

Cathrin Brisken, Dalya Ataca

Most of mammary gland development occurs postnatally under the control of female reproductive hormones, which in turn interact with other endocrine factors. While hormones impinge on many tissues and trigger very complex biological responses, tissue recomb ...

Wiley-Blackwell2015

Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk

Cathrin Brisken, Jacques Rougemont, Ayyakkannu Ayyanan, Marian Caikovski, Renuga Devi Rajaram, Duje Buric

Ovarian hormones increase breast cancer risk by poorly understood mechanisms. We assess the role of progesterone on global stem cell function by serially transplanting mouse mammary epithelia. Progesterone receptor (PR) deletion severely reduces the regene ...

Wiley-Blackwell2015

In Vitro Pancreas Organogenesis from Dispersed Mouse Embryonic Progenitors

Filippo De Franceschi, Anne Grapin-Botton, Chiara Greggio

The pancreas is an essential organ that regulates glucose homeostasis and secretes digestive enzymes. Research on pancreas embryogenesis has led to the development of protocols to produce pancreatic cells from stem cells. The whole embryonic organ can be c ...

Journal Of Visualized Experiments2014

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Duct (anatomy)

Estrogen receptor signaling in the human breast epithelium

Membrane expression of the estrogen receptor ER alpha is required for intercellular communications in the mammary epithelium

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

Oestrogen receptor alpha AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium

Progesterone and Overlooked Endocrine Pathways in Breast Cancer Pathogenesis

Cell Cycle-Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas

Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis

Endocrine hormones and local signals during the development of the mouse mammary gland

Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk

In Vitro Pancreas Organogenesis from Dispersed Mouse Embryonic Progenitors

Graph Chatbot

Chat with Graph Search

Membrane expression of the estrogen receptor ER alpha is required for intercellular communications in the mammary epithelium

Endocrine hormones and local signals during the development of the mouse mammary gland

Estrogen receptor signaling in the human breast epithelium

Progesterone and Overlooked Endocrine Pathways in Breast Cancer Pathogenesis

Cell Cycle-Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas

Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk

In Vitro Pancreas Organogenesis from Dispersed Mouse Embryonic Progenitors

Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

Oestrogen receptor alpha AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium