Concept

Population ageing

Related publications (141)

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART

Jacques Fellay, Christian Axel Wandall Thorball, Alessandro Borghesi

The HIV-1 reservoir is the major hurdle to a cure. We here evaluate viral and host characteristics associated with reservoir size and long-term dynamics in 1,057 individuals on suppressive antiretroviral therapy for a median of 5.4 years. At the population ...

Springer2019

The Scale-Dependent Behaviour of Cities: A Cross-Cities Multiscale Driver Analysis of Urban Energy Use

Franziska Meinherz, Aristide Henri Roger Athanassiadis, João Vitor Meirelles de Miranda

Hosting more than half of the world population, cities are currently responsible for two thirds of the global energy use and three quarters of the global CO2 emissions related to energy use. As humanity becomes more urbanized, urban systems are becoming a ...

2019

Wastewater management towards a sustainable futureDairy production: a study case

François Maréchal, Ivan Daniel Kantor, Rafael Amorim Leandro De Castro Amoedo, Anna Sophia Wallerand, Hür Ebuzer Bütün

The increasing demand for heat, electricity, fuels and chemicals is pushing naturalresources towards a non-reversible situation. Current solutions have to be adapted,and alternative (desirably sustainable) sources have to be found. With growth as-sured due ...

Institute of Thermal Technology, Silesian University of Technology2019

Latest advances in aging research and drug discovery

Andrea Ablasser

An increasing aging population poses a significant challenge to societies worldwide. A better understanding of the molecular, cellular, organ, tissue, physiological, psychological, and even sociological changes that occur with aging is needed in order to t ...

IMPACT JOURNALS LLC2019

Socio-economic determinants of sprawl: causes and consequences of urban growth in Swiss municipalities

Barbara Franziska Weilenmann

In Switzerland, as elsewhere, over the past decades, urban areas have spread outwards â consuming the surrounding countryside in the process. The result has been an urban growth associated with negative effects such as the loss of cultivated land. Sprawl ...

EPFL2019

Mechanics of Allostery: Contrasting the Induced Fit and Population Shift Scenarios

Matthieu Wyart, Carolina Brito Carvalho dos Santos, Solange Marie Flatt, Stefano Zamuner, Riccardo Ravasio

In allosteric proteins, binding a ligand can affect function at a distant location, for example, by changing the binding affinity of a substrate at the active site. The induced fit and population shift models, which differ by the assumed number of stable c ...

CELL PRESS2019

Magnitude of urban heat islands largely explained by climate and population

Gabriele Manoli, Gabriel George Katul, Paolo Burlando

Urban heat islands (UHIs) exacerbate the risk of heat-related mortality associated with global climate change. The intensity of UHIs varies with population size and mean annual precipitation, but a unifying explanation for this variation is lacking, and th ...

2019

Mitochondria! function is impaired in the skeletal muscle of pre-frail elderly

Johan Auwerx, Pénélope Andreux

Aging is accompanied by a gradual decline in both muscle mass and strength over time, which can eventually lead to pathologies, such as frailty and sarcopenia. While these two conditions are well characterized, further investigation of the early biological ...

2018

Alternative Urban Planning for Poor Cities in Africa

Jean-Claude Bolay

The efforts made to plan cities in emerging and developing countries are confronted to multiple issues, especially in small and middle-sized cities, which can be considered as poor through several criteria: socio-economic level of majority of population; l ...

2018

Robust model updating methodology for estimating worst-case load capacity of existing bridges

Ian Smith, Didier Vernay, François-Xavier Favre

High-value infrastructure elements, such as bridges, are typically over-designed. Model-updating techniques are useful for estimating the reserve load capacity (beyond safety factors) of bridges and this improves sustainability through good asset-managemen ...

2018

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.