Related publications (43)

Meeting our Makers:Uncovering the cis-regulatory activity of transposable elements using statistical learning

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The adaptation of organisms to their environment depends on the innovative potential inherent to genetic variation. In complex organisms such as mammals, processes like development and immunity require tight gene regulation. Complex forms emerge more often ...
EPFL2024

Understanding the Mechanobiology of Early Mammalian Development through Bioengineered Models

Matthias Lütolf, Stefano Davide Vianello

Research in developmental biology has been recently enriched by a multitude of in vitro models recapitulating key milestones of mammalian embryogenesis. These models obviate the challenge posed by the inaccessibility of implanted embryos, multiply experime ...
2019

Robust Baseline Measurement for Reliable Fetal Heart Rate Evaluation

Guglielmo Frigo

Cardiotocography is a measurement technique widely adopted to assess fetal well-being during both antepartum and intra-partum stages. It consists of two simultaneously acquired time-series: fetal heart rate and uterine activity. Since visual inspection ana ...
IEEE2018

Lab-on-a-chip technologies for manipulation and imaging of C. elegans worms and embryos

Li Dong

The nematode Caenorhabditis elegans is an attractive model organism, owing notably to its short life cycle, genetic tractability, and optical transparency facilitating microscopic observation. This thesis deals with the realization of technological tools f ...
EPFL2018

Segmentation of Developing Human Embryo in Time-lapse Microscopy

Mathieu Salzmann

Being able to efficiently segment a developing embryo from background clutter constitutes an important step in automated monitoring of human embryonic cells. State-of-the-art automatic segmentation methods remain ill-suited to handle the complex behavior a ...
IEEE2016

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