Publications related to Chemotaxis

Multiscale Porosity Microfluidics to Study Bacterial Transport in Heterogeneous Chemical Landscapes

Microfluidic models are proving to be powerful systems to study fundamental processes in porous media, due to their ability to replicate topologically complex environments while allowing detailed, quantitative observations at the pore scale. Yet, while por ...

Hoboken2024

A generic diffusion-based approach for 3D human pose prediction in the wild

Alexandre Massoud Alahi, Saeed Saadatnejad, Taylor Ferdinand Mordan

Predicting 3D human poses in real-world scenarios, also known as human pose forecasting, is inevitably subject to noisy inputs arising from inaccurate 3D pose estimations and occlusions. To address these challenges, we propose a diffusion-based approach th ...

IEEE2023

Computational design of ultrasensitive flexible peptide:receptor signaling complexes for enhanced chemotaxis

Patrick Daniel Barth, Mahdi Hijazi, Aurélien Laurent Jean-Charles Oggier, Ana Paola Rico Villarreal, Robert Everett Jefferson, Andreas Füglistaler

Engineering biosensors that sensitively recognize specific biomolecules and trigger functional cellular responses is a holy grail of diagnostics and synthetic cell biology. Biosensor design approaches have mostly focused on binding structurally well-define ...

bioRxiv2022

Characterization of Pseudomonas aeruginosa mechanosensing through label-free imaging of type IV pili

Lorenzo Anton-Louis Talà

Bacteria are ubiquitously found in all sorts of environment. They're found in the ocean, soil, or even in our guts or on our skin. Independently of their niche, they can transition from a planktonic state were they freely swim in an aqueous environment to ...

EPFL2022

Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion

Douglas Hanahan, Nadine Fournier, Krisztian Homicsko, Mélanie Louise Tichet, Agnieszka Alicja Chryplewicz, Jeremy Gilles Louis Guillot, Simge Yücel, Mohammad Sadegh Saghafinia, Inti Zlobec, Yuqing Xie, Dalya Ataca, Qiqun Zeng, Fleuriane Marie Tryskele Laurene Gallean, Peng Zhang, Lucine Christe

Many human cancers manifest the capability to circumvent attack by the adaptive immune system. In this work, we identified a component of immune evasion that involves frequent up-regulation of fragile X mental retardation protein (FMRP) in solid tumors. FM ...

Washington2022

Preexisting Heterogeneity of Inducible Nitric Oxide Synthase Expression Drives Differential Growth of Mycobacterium tuberculosis in Macrophages

John McKinney, Ophélie Rutschmann, Chiara Toniolo

Mycobacterium tuberculosis infection is initiated by the inhalation and implantation of bacteria in the lung alveoli, where they are phagocytosed by macrophages. Even a single bacterium may be sufficient to initiate infection. Thereafter, the clinical outc ...

AMER SOC MICROBIOLOGY2022

Mechanotaxis directs Pseudomonas aeruginosa twitching motility

Alexandre Louis André Persat, Lorenzo Anton-Louis Talà, Xavier Jean-Yves Pierrat, Jose Negrete Jr, Joanne Netter Engel, Marco Julian Kühn

The opportunistic pathogen Pseudomonas aeruginosa explores surfaces using twitching motility powered by retractile extracellu-lar filaments called type IV pili (T4P). Single cells twitch by sequen-tial T4P extension, attachment, and retraction. How single ...

NATL ACAD SCIENCES2021

Small peptide diversification through photoredox-catalyzed oxidative C-terminal modification

Jérôme Waser, Eliott Hugo Joran Le Du, Marion Marie-Agnès Garreau

A photoredox-catalyzed oxidative decarboxylative coupling of small peptides is reported, giving access to a variety of N,O-acetals. They were used as intermediates for the addition of phenols and indoles, leading to novel peptide scaffolds and bioconjugate ...

2021

Spatiotemporal pattern formation in E. coli biofilms explained by a simple physical energy balance

Anne-Florence Raphaëlle Bitbol

While the biofilm growth mode conveys notable thriving advantages to bacterial populations, the mechanisms of biofilm formation are still strongly debated. Here, we investigate the remarkable spontaneous formation of regular spatial patterns during the gro ...

Royal Society of Chemistry (RSC)2020

Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae

Beatrice Volpe, Julia Esser-von Bieren, Tiffany Babette Angélique Bouchery, Kathleen Shah

Helminth infection represents a major health problem causing approximately 5 million disability-adjusted life years worldwide. Concerns that repeated anti-helminthic treatment may lead to drug resistance render it important that vaccines are developed but ...

WILEY2020

Chemotaxis

Multiscale Porosity Microfluidics to Study Bacterial Transport in Heterogeneous Chemical Landscapes

A generic diffusion-based approach for 3D human pose prediction in the wild

Computational design of ultrasensitive flexible peptide:receptor signaling complexes for enhanced chemotaxis

Characterization of Pseudomonas aeruginosa mechanosensing through label-free imaging of type IV pili

Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion

Preexisting Heterogeneity of Inducible Nitric Oxide Synthase Expression Drives Differential Growth of Mycobacterium tuberculosis in Macrophages

Mechanotaxis directs Pseudomonas aeruginosa twitching motility

Small peptide diversification through photoredox-catalyzed oxidative C-terminal modification

Spatiotemporal pattern formation in E. coli biofilms explained by a simple physical energy balance

Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae

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Small peptide diversification through photoredox-catalyzed oxidative C-terminal modification

Spatiotemporal pattern formation in E. coli biofilms explained by a simple physical energy balance

Multiscale Porosity Microfluidics to Study Bacterial Transport in Heterogeneous Chemical Landscapes

Computational design of ultrasensitive flexible peptide:receptor signaling complexes for enhanced chemotaxis

Mechanotaxis directs Pseudomonas aeruginosa twitching motility

Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae

A generic diffusion-based approach for 3D human pose prediction in the wild

Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion

Characterization of Pseudomonas aeruginosa mechanosensing through label-free imaging of type IV pili

Preexisting Heterogeneity of Inducible Nitric Oxide Synthase Expression Drives Differential Growth of Mycobacterium tuberculosis in Macrophages