Concept

Graft (surgery)

Related publications (29)

Device design and materials optimization of conformal coating for islets of Langerhans

Encapsulation of islets of Langerhans may represent a way to transplant islets in the absence of immunosuppression. Traditional methods for encapsulation lead to diffusional limitations imposed by the size of the capsules (600-1,000 m in diameter), which r ...

Natl Acad Sciences2014

Advances in the design of macroporous polymer scaffolds for potential applications in dentistry

Philippe Renaud, Thomas Michael Braschler, Sidi Ahmed Bencherif

A paradigm shift is taking place in medicine and dentistry from using synthetic implants and tissue grafts to a tissue engineering approach that uses degradable porous three-dimensional (3D) material hydrogels integrated with cells and bioactive factors to ...

2013

Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning

Matthias Lütolf, Adrian Ranga, Martin Ehrbar

Engineered artificial microenvironments hold enormous potential as models to study developmental, physiological, pathological, and regenerative processes under highly defined conditions. Such platforms aim at bridging the gap between traditional in vitro 2 ...

2011

Biomechanical, morphological and zero-stress state characterization of jugular vein remodeling in arteriovenous fistulas for hemodialysis

Nikolaos Stergiopoulos

While the role of hemodynamic variables on the development of intimal hyperplasia in arteriovenous fistulas for hemodialysis has been examined, less is known about the intramural biomechanical factors. In this study, arteriovenous fistulas were created by ...

2010

Bone healing induced by local delivery of an engineered parathyroid hormone prodrug

Jeffrey Alan Hubbell

Regenerative medicine requires innovative therapeutic designs to accommodate high morphogen concentrations in local depots, provide their sustained presence, and enhance cellular invasion and directed differentiation. Here we present an example for inducin ...

2009

Motional heterogeneity in single-site silica-supported species revealed by deuteron NMR

David Lyndon Emsley

The molecular dynamics of [-SiDMe(2)] grafted on two amorphous silica materials, mesoporous SBA and non-porous Aerosil, was investigated by deuteron ((2)H) solid-state NMR spectroscopy. Quadrupole echo (QE), quadrupole Carr-Purcell-Meiboom-Gill (QCPMG) and ...

ROYAL SOC CHEMISTRY2009

Theroretical and experimental multi-scale study of an artificial bone construct

Luc Blecha

Synthetic bone substitutes are potentially the future gold standard in orthopaedic and traumatologic surgery. The availability of these bone substitutes with different biomechanical properties may well replace autografts in the future as they overcome comp ...

EPFL2007

Architecture and properties of anisotropic polymer composite scaffolds for bone tissue engineering

Dominique Pioletti, Pierre-Etienne Bourban

Bone is a complex porous composite structure with specific characteristics such as viscoelasticity and anisotropy, both in morphology and mechanical properties. Bone defects are regularly filled with artificial tissue grafts, which should ideally have prop ...

2006

Protein-functionalized polymer brushes

Harm-Anton Klok, Kai Johnsson, Stefano Tugulu, India Christina Sielaff, Anke Arnold

Understanding and controlling the interactions between synthetic and biol. materials is of great importance for the development of novel materials for a variety of biomedical and bioanal. applications, including for example stents, vascular grafts and prot ...

2005

Effects of the posterior cruciate ligament reconstruction on the biomechanics of the knee joint: a finite element analysis

Alexandre Terrier

Background. Previous experimental studies have been conducted to evaluate the biomechanical effects of posterior cruciate ligament reconstruction; but no consensus has been reached on the preferred method of reconstruction. Methods. The 3D finite element m ...

2005

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