Concept

Breast milk

Related publications (33)

Does Cancer Start in the Womb? Altered Mammary Gland Development and Predisposition to Breast Cancer due to in Utero Exposure to Endocrine Disruptors

We are now witnessing a resurgence of theories of development and carcinogenesis in which the environment is again being accepted as a major player in phenotype determination. Perturbations in the fetal environment predispose an individual to disease that ...

Springer Verlag2013

Validation of an in vitro digestive system for studying macronutrient decomposition in humans

Martinus Gijs, Guy Vergères, Flurina Schwander, Reto Portmann

The digestive process transforms nutrients and bioactive compounds contained in food to physiologically active compounds. In vitro digestion systems have proven to be powerful tools for understanding and monitoring the complex transformation processes that ...

2012

Sustainability solution space of the Swiss milk value added chain

Claudia Rebeca Binder Signer, Alexandre Schmid

Current indicator-based sustainability assessment approaches usually have three shortcomings: (i) ecological as- pects are mostly overrepresented in relation to importance and complexity of economic and social aspects; (ii) they center on filling important ...

Elsevier2012

Nutrichip: an integrated microfluidic system for in vitro investigation of the immunemodulatory function of dairy products

Martinus Gijs, Sandro Carrara, Paolo Silacci, Hamideh Jafarpoorchekab, Guy Vergères, Flurina Schwander

We introduce the concept of the NutriChip, a miniaturized artificial human gastrointestinal tract (GIT) for investigating the potential of immuno-modulatory function of dairy food. More specifically, we are investigating the effect of digested milk on immu ...

2011

High hopes for RANKL: will the mouse model live up to its promise?

Cathrin Brisken, Tamara Tanos

The steroid hormones, estrogens and progesterone are key drivers of postnatal breast development and are linked to breast carcinogenesis. Experiments in the mouse mammary gland have revealed that they rely on paracrine factors to relegate their signal loca ...

BioMed Central2011

Cyclin D1 Enhances the Response to Estrogen and Progesterone by Regulating Progesterone Receptor Expression

Cathrin Brisken

Estrogen and progesterone are the defining hormones of normal female development, and both play critical roles in breast carcinogenesis. Cyclin D1 is a breast cancer oncogene whose amplification is linked to poor prognosis in estrogen and progesterone rece ...

American Society for Microbiology2010

Role of canonical Wnt signaling in mammary gland development

Renuga Devi Rajaram

The female reproductive hormones estrogens, progesterone, and prolactin control postnatal breast development and are important to breast carcinogenesis. In particular, exposure to progesterone is tightly linked to breast cancer risk. Using the mouse as a m ...

EPFL2010

Occurrence of persistent toxic substances in soils, sediments, fishes and human breast milk in southern Vietnam

Ngoc Vinh Nguyen

Global contamination and toxic effects of persistent toxic substances (PTSs) have been an emerging environmental issue and have received considerable attention during the past four decades. The rapid agricultural and industrial growths as well as the expan ...

EPFL2009

Hormonal regulation of Stat5 in the mammary gland - from signaling to morphogenesis

Sergio Klinke

The mammary gland development is regulated by steroid and peptide hormones and occurs mainly after birth, compared to the majority of the other organs in the body. The principal hormones responsible for the breast development are the estrogen, the progeste ...

2008

Endocrine Disruptors and Breast Cancer

Cathrin Brisken

Breast cancer strikes one out of eight women in Switzerland. The increase in breast cancer incidence over the past 70 years parallels an enormous increase of man-made, persistent chemicals in our environment; some of which have endocrine-disrupting propert ...

2008

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