Concept

William Bosworth Castle

Summary
William Bosworth Castle (October 21, 1897 – August 9, 1990) was an American physician and physiologist who transformed hematology from a "descriptive art to a dynamic interdisciplinary science." Life Castle was born to William E. Castle and his wife in Cambridge, Massachusetts. His father was a professor of zoology at Harvard, a pioneer in mammalian genetics, and a member of the U.S. National Academy of Sciences. The young Castle was educated in local schools and entered Harvard College in 1914. At the end of his third year of college, he enrolled in Harvard Medical School. Upon graduating from medical school, he did a medical internship at the Massachusetts General Hospital from 1921-1923. At the Mass General, he had his first direct exposure to some of the great clinicians of the time, including Chester M. Jones, with whom he collaborated on his first medical publication, and George R. Minot, who later became Castle's mentor and unflagging supporter. (Minot later shared th
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