Concept

Dendrite

Related publications (132)

Morphological development of thick-tufted layer v pyramidal cells in the rat somatosensory cortex

Henry Markram, Yun Wang, Sandrine Romand

The thick-tufted layer V pyramidal (TTL5) neuron is a key neuron providing output from the neocortex. Although it has been extensively studied, principles governing its dendritic and axonal arborization during development are still not fully quantified. Us ...

2011

Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties

Henry Markram, Felix Schürmann, Sean Lewis Hill, Idan Segev

The thick-tufted layer 5b pyramidal cell extends its dendritic tree to all six layers of the mammalian neocortex and serves as a major building block for the cortical column. L5b pyramidal cells have been the subject of extensive experimental and modeling ...

2011

Interregional synaptic competition in neurons with multiple STDP-inducing signals

Idan Segev

Neocortical layer 5 (L5) pyramidal cells have at least two spike initiation zones: Na+ spikes are generated near the soma, and Ca2+ spikes at the apical dendritic tuft. These spikes interact with each other and serve as signals for synaptic plasticity. The ...

2011

Interregional synaptic competition in neurons with multiple STDP-inducing signals

Idan Segev

Neocortical layer 5 (L5) pyramidal cells have at least two spike initiation zones: Na(+) spikes are generated near the soma, and Ca(2+) spikes at the apical dendritic tuft. These spikes interact with each other and serve as signals for synaptic plasticity. ...

American Physiological Society2011

The Dynamics of Adapting Neurons

Richard Naud

How do neurons dynamically encode and treat information? Each neuron communicates with its distinctive language made of long silences intermitted by occasional spikes. The spikes are prompted by the pooled effect of a population of pre-synaptic neurons. To ...

EPFL2011

Diffraction-unlimited all-optical imaging and writing with a photochromic GFP

Marcel Leutenegger

Lens-based optical microscopy failed to discern fluorescent features closer than 200 nm for decades, but the recent breaking of the diffraction resolution barrier by sequentially switching the fluorescence capability of adjacent features on and off is maki ...

2011

Inhibitory Plasticity Balances Excitation and Inhibition in Sensory Pathways and Memory Networks

Wulfram Gerstner, Friedemann Zenke, Claudia Clopath, Tim Vogels

Cortical neurons receive balanced excitatory and inhibitory synaptic currents. Such a balance could be established and maintained in an experience-dependent manner by synaptic plasticity at inhibitory synapses. We show that this mechanism provides an expla ...

2011

Simulations to study spatial extent of stimulation and effect of electrode–tissue gap in subretinal implants

Philippe Renaud, Arnaud Bertsch, Sri Harsha Kasi Raj

We present a finite element based simulation and analysis method to describe the spatial extent of stimulation and the effects of electrode–tissue interactions in subretinal prostheses. In particular, we estimate the threshold stimulation current needed to ...

Elsevier2011

Connectivity reflects coding: a model of voltage-based STDP with homeostasis

Wulfram Gerstner, Eleni Vasilaki, Claudia Clopath

Electrophysiological connectivity patterns in cortex often have a few strong connections, which are sometimes bidirectional, among a lot of weak connections. To explain these connectivity patterns, we created a model of spike timing–dependent plasticity (S ...

Nature Publishing Group2010

Au-Fe alloy solidification and solid-state transformations

Michel Rappaz, Jean-Daniel Wagnière

In order to better understand the microstructure that forms during laser welding of an 18 carat gold and an austenitic stainless steel, solidification of the Au-Fe binary analog has been studied using thermal analysis and interrupted Bridgman experiments. ...

Elsevier2010

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