Concept

Glutathione

Related publications (68)

Computational Evidence for the Catalytic Mechanism of Human Glutathione S Transferase A3-3. A QM/MM Investigation

A Quantum Mechanics/Molecular Mechanics (QM/MM) computational investigation of the catalytic mechanism of the human glutathione transferase A3-3 (hGSTA3-3) has been carried out. The results demonstrate that the isomerization reaction is concerted, but high ...

2012

Metal accumulation and response of antioxidant enzymes in seedlings and adult sunflower mutants with improved metal removal traits on a metal-contaminated soil

Jean-Paul Schwitzguebel, Erika Nehnevajova

Sunflower mutant lines with an enhanced tolerance and metal accumulation capacity obtained by mutation breeding have been proposed for Zn, Cd and Cu removal from metal-contaminated soils in previous studies. However, soils contaminated with trace elements ...

Elsevier2012

Highly cytotoxic trithiophenolatodiruthenium complexes of the type [(eta(6)-p-MeC6H4Pr (i) )(2)Ru-2(SC6H4-p-X)(3)](+): synthesis, molecular structure, electrochemistry, cytotoxicity, and glutathione oxidation potential

Paul Joseph Dyson, Olivier Pierre Zava, Mathurin Baquié

A series of cationic dinuclear p-cymene ruthenium trithiophenolato complexes of the type (eta(6)-p-MeC6H4Pr (i) )(2)Ru-2(SC6H4-p-X)(3) (1 X is H, 2 X is Me, 3 X is Ph, 4 X is Br, 5 X is OH, 6 X is NO2, 7 X is OMe, 8 X is CF3, 9 X is F, 10 X is Pr (i) ...

2012

Biomimetic Oxygen Reduction by Cofacial Porphyrins at a Liquid-Liquid Interface

Hubert Girault, Pekka Eero Peljo

Oxygen reduction catalyzed by cofacial metalloporphyrins at the 1,2-dichlorobenzene-water interface was studied with two lipophilic electron donors of similar driving force, 1,1'-dimethylferrocene (DMFc) and tetrathiafulvalene (TTF). The reaction produces ...

2012

Accumulation of pollutants and plant wellness : Bottleneck or key to successful phytoremediation ?

Jean-Paul Schwitzguebel

Because plants are static and live in a competitive and sometimes hostile environment, they have evolved mechanisms that protect them from abiotic and biotic stress. These mechanisms include detoxification and sequestration of xenobiotic compounds and of h ...

2011

Altered Glycogen Metabolism in Cultured Astrocytes from Mice with Chronic Glutathione Deficit; Relevance for Neuroenergetics in Schizophrenia

Pierre Magistretti, Igor Allaman, Kim Do, Jean-Marie Petit

Neurodegenerative and psychiatric disorders including Alzheimer's, Parkinson's or Huntington's diseases and schizophrenia have been associated with a deficit in glutathione (GSH). In particular, a polymorphism in the gene of glutamate cysteine ligase modul ...

Public Library of Science2011

Plant accumulation of pollutants versus plant wellness: insoluble conundrum or key to a successful green clean-up?

Jean-Paul Schwitzguebel

2010

Molecular electrocatalysis at soft interfaces

Hubert Girault

The fundamental aspects of electrochemistry at liquid–liquid interfaces are introduced to present the concept of molecular electrocatalysis. Here, a molecular catalyst is adsorbed at the interface to promote a proton coupled electron transfer reaction such ...

Royal Society of Chemistry2010

Dualities in plant tolerance to pollutants and their uptake and translocation to the upper plant parts

Jean-Paul Schwitzguebel

There is a duality in plant tolerance to pollutants and its response to the pollutants’ stress. On the one hand some plants, (hyper)tolerant to heavy metals, are able to hyperaccumulate these metals in shoots, which could be beneficial for phytoremediation ...

2009

Comparison of T-1 Relaxation Times of the Neurochemical Profile in Rat Brain at 9.4 Tesla and 14.1 Tesla

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

Knowledge of T-1 relaxation times can be important for accurate relative and absolute quantification of brain metabolites, for sensitivity optimizations, for characterizing molecular dynamics, and for studying changes induced by various pathological condit ...

Wiley-Blackwell2009

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