The Loire Valley (Val de Loire, val də lwaʁ; Traoñ al Liger), spanning , is a valley located in the middle stretch of the Loire river in central France, in both the administrative regions Pays de la Loire and Centre-Val de Loire. The area of the Loire Valley comprises about . It is referred to as the Cradle of the French and the Garden of France due to the abundance of vineyards, fruit orchards (such as cherries), and artichoke, and asparagus fields, which line the banks of the river. Notable for its historic towns, architecture, and wines, the valley has been inhabited since the Middle Palaeolithic period. The oldest known Neanderthal engravings have been found a cave in La Roche-Cotard which have been dated to more than 57,000 years ago. In 2000, UNESCO added the central part of the Loire River valley to its list of World Heritage Sites. The valley includes historic towns such as Amboise, Angers, Blois, Chinon, Montsoreau, Orléans, Saumur, and Tours. The climate is favorable most of the year, the river often acting as a line of demarcation in France's weather between the northern climate and the southern. The river has a significant effect on the mesoclimate of the region, adding a few degrees of temperature. The climate can be cool with springtime frost while wine harvest months may have rain. Summers are hot; however, influences from the Atlantic moderate the temperature with breezes. Loire Valley (wine) The Loire Valley wine region is one of the world's most well-known areas of wine production and includes several French wine regions situated along the river, from the Muscadet region on the Atlantic coast to the regions of Sancerre and Pouilly-Fumé just southeast of the city of Orléans in north-central France. Loire wines tend to exhibit a characteristic fruitiness with fresh, crisp flavors. On 2 December 2000, UNESCO added the central part of the river valley, between Chalonnes-Sur-Loire and Sully-sur-Loire, to its list of World Heritage Sites.