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The study aim was to quantify the individual and combined contributions of both the arterial system and the heart to systolic blood pressure in hypertension. We assessed the parameters of a heart-arterial model for normotensive control subjects and hyperte ...
Compounds which are PPAR delta agonists are described. These compounds are useful for raising high density lipoprotein (HDL) plasma levels in mammals and for preventing, halting or slowing the progression of atherosclerotic cardiovascular diseases and rela ...
The micro structure and mechanical properties of a high volume fraction SiC particle reinforced AlCu4MgAg alloy produced by squeeze pressurised infiltration of dense packed particle preforms were characterised. It was found that the addition of 60 vol.% 12 ...
This study aimed to model phenomenologically the dynamics of arterial wall remodeling under hypertensive conditions. Sustained hypertension was simulated by a step increase in blood pressure. The arterial wall was considered to be a thick-walled tube made ...
Medicine is one of the branches of scientific research in which numerical simulation can give a great support. In particular, a well mature branch like computational fluid dynamics (CFD) can provide a substantial help for the understanding of several patho ...
Bristeau, M.-O. (ed.) et al. Chichester: John Wiley & Sons.1997
We previously reported that change, with age, in plasma levels of total cholesterol (TC) and LDL cholesterol (LDL-C) differed between apolipoprotein E (APOE) genotypes epsilon 3 epsilon 3 and epsilon 3 epsilon 4, in a sample of 77 older, unrelated males. B ...
A finite element model of the human carotid bifurcation was developed to investigate the possibility that pressure-induced arterial wall stresses lead to the formation of atherosclerosis. The effect of material non-homogeneity was investigated by measuring ...
Shows how numerical solutions of the human cardiovascular system may be devised by coupling models having different physical dimensions. One of the aspects of the circulatory system is its multiscale nature. Local flow features may have a global effect on ...
The peroxisome proliferator-activated receptor gamma (PPARgamma) is a ligand-dependent transcription factor that has been demonstrated to regulate fat cell development and glucose homeostasis. PPARgamma is also expressed in a subset of macrophages and nega ...
A three-dimensional finite element model of the carotid artery bifurcation was constructed in order to determine the stress field and assess the modification of the stress field when residual strain is taken into account. Residual strain in the carotid bif ...