Concept

Multiple organ dysfunction syndrome

Related publications (17)

Gut physiology mediates a trade-off between adaptation to malnutrition and susceptibility to food-borne pathogens

Bruno Lemaitre, Sveta Chakrabarti, Sylvain Kolly

The animal gut plays a central role in tackling two common ecological challenges, nutrient shortage and food-borne parasites, the former by efficient digestion and nutrient absorption, the latter by acting as an immune organ and a barrier. It remains unkno ...

Wiley-Blackwell2015

Positive network assortativity of influenza vaccination at a high school: implications for outbreak risk and herd immunity

Marcel Salathé

Schools are known to play a significant role in the spread of influenza. High vaccination coverage can reduce infectious disease spread within schools and the wider community through vaccine-induced immunity in vaccinated individuals and through the indire ...

Public Library of Science2014

Intravital Immunofluorescence for Visualizing the Microcirculatory and Immune Microenvironments in the Mouse Ear Dermis

Melody Swartz, Witold Waldemar Kilarski, Amanda Waite Lund, Jeremy Teo, Scott Oliver

Visualizing the dynamic behaviors of immune cells in living tissue has dramatically increased our understanding of how cells interact with their surroundings, contributing important insights into mechanisms of leukocyte trafficking, tumor cell invasion, an ...

Public Library of Science2013

Long-range activation of systemic immunity through peptidoglycan diffusion in Drosophila

Bruno Lemaitre, David Welchman

The systemic immune response of Drosophila is known to be induced both by septic injury and by oral infection with certain bacteria, and is characterized by the secretion of antimicrobial peptides (AMPs) into the haemolymph. To investigate other possible r ...

2009

Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection

Nicola Harris, Andrew J. Macpherson

Anti-helminth immunity involves CD4+ T cells, yet the precise effector mechanisms responsible for parasite killing or expulsion remain elusive. We now report an essential role for antibodies in mediating immunity against the enteric helminth Heligmosomoide ...

2008

The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila

Bruno Lemaitre

Septic injury triggers a rapid and widespread response in Drosophila adults that involves the up-regulation of many genes required to combat infection and for wound healing. Genome-wide expression profiling has already demonstrated that this response is co ...

Wiley-Blackwell2006

Defective host defence mechanisms in a family with hypocalciuric hypercalcaemia and coexisting interstitial lung disease

Johan Auwerx

An extensive in vitro investigation of the host defence system was performed in 11 sibs of a large kindred with unexplained combination of familial hypocalciuric hypercalcaemia (FHH), interstitial lung disease and increased susceptibility to respiratory in ...

1985

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