Publications related to Bile | EPFL Graph Search

The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice

Kristina Schoonjans

BACKGROUND & AIMS: Abnormal delivery of bile acids (BAs) to the colon as a result of disease or therapy causes constipation or diarrhea by unknown mechanisms. The G protein-coupled BA receptor TGR5 (or GPBAR1) is expressed by enteric neurons and endocrine ...

W B Saunders Co-Elsevier Inc2013

Double-balloon jejunal perfusion to compare absorption of vitamin E and vitamin E acetate in healthy volunteers under maldigestion conditions

Martin Kussmann, Krisztina Nagy

BACKGROUND/OBJECTIVES: The vitamin E derivative, alpha-tocopheryl acetate, is often included in formulations used in enteral nutrition. In this respect, we compared alpha-tocopherol and alpha-tocopheryl acetate absorption under 'maldigestion' conditions, s ...

Nature Publishing Group2013

Probing the Binding Site of Bile Acids in TGR5

Johan Auwerx, Kristina Schoonjans, Thijs Pols

TGR5 is a G-protein-coupled receptor (GPCR) mediating cellular responses to bile acids (BAs). Although some efforts have been devoted to generate homology models of TGR5 and draw structure-activity relationships of BAs, none of these studies has hitherto d ...

American Chemical Society2013

Superior sensing performance of multi-walled carbon nanotube-based electrodes to detect unconjugated bilirubin

Giovanni De Micheli, Sandro Carrara, Irene Taurino

The direct electrochemical behaviour of bilirubin in the physio-pathological concentration range and at physio- logical pH was investigated by cyclic voltammetry. Nanostructured electrodes with a thin film of multi-walled carbon nanotubes exhibited a highe ...

Elsevier2013

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins

Johan Auwerx, Kristina Schoonjans, Mitsunori Nomura, Thijs Pols, Taoufiq Harach, Adriano Maida

Anionic exchange resins are bona fide cholesterol-lowering agents with glycemia lowering actions in diabetic patients. Potentiation of intestinal GLP-1 secretion has been proposed to contribute to the glycemia lowering effect of these non-systemic drugs. H ...

2012

Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure

Johan Auwerx, Kristina Schoonjans, Chikage Mataki

Besides well-established roles of bile acids (BA) in dietary lipid absorption and cholesterol homeostasis, it has recently become clear that BA is also a biological signaling molecule. We have shown that strategies aimed at activating TGR5 by increasing th ...

Public Library of Science2012

In situ investigation of dye adsorption on TiO2 films using a quartz crystal microbalance with a dissipation technique

Michael Graetzel, Nicolas Tétreault, Hauke Arne Harms, Bengt Kasemo

Dye adsorption plays a crucial role in dye-sensitized solar cells. Herein, we demonstrate an in situ liquid- phase analytical technique to quantify in real time adsorption of dye and coadsorbates on flat and mesoporous TiO2 films. For the first time, a mol ...

2012

The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

Johan Auwerx, Kristina Schoonjans, Lilia Noriega Lopez, Mitsunori Nomura, Thijs Pols

Bile acids (BAs) are amphipathic molecules that facilitate the uptake of lipids, and their levels fluctuate in the intestine as well as in the blood circulation depending on food intake. Besides their role in dietary lipid absorption, bile acids function a ...

Elsevier2011

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Bile

The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice

The Receptor TGR5 Protects the Liver From Bile Acid Overload During Liver Regeneration in Mice

Double-balloon jejunal perfusion to compare absorption of vitamin E and vitamin E acetate in healthy volunteers under maldigestion conditions

Bile Acids Increase Levels of MicroRNAs 221 and 222, Leading to Degradation of CDX2 During Esophageal Carcinogenesis

Probing the Binding Site of Bile Acids in TGR5

Superior sensing performance of multi-walled carbon nanotube-based electrodes to detect unconjugated bilirubin

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins

Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure

In situ investigation of dye adsorption on TiO2 films using a quartz crystal microbalance with a dissipation technique

The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

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The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice

The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

The Receptor TGR5 Protects the Liver From Bile Acid Overload During Liver Regeneration in Mice

Superior sensing performance of multi-walled carbon nanotube-based electrodes to detect unconjugated bilirubin

Bile Acids Increase Levels of MicroRNAs 221 and 222, Leading to Degradation of CDX2 During Esophageal Carcinogenesis

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins

Probing the Binding Site of Bile Acids in TGR5

Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure

In situ investigation of dye adsorption on TiO2 films using a quartz crystal microbalance with a dissipation technique

Double-balloon jejunal perfusion to compare absorption of vitamin E and vitamin E acetate in healthy volunteers under maldigestion conditions