Circumcision is a procedure that removes the foreskin from the human penis. In the most common form of the operation, the foreskin is extended with forceps, then a circumcision device may be placed, after which the foreskin is excised. Topical or locally injected anesthesia is generally used to reduce pain and physiologic stress. Circumcision is generally electively performed, most commonly done as a form of preventive healthcare, as a religious obligation, or as a cultural practice. It is also an option for cases of phimosis, other pathologies that do not resolve with other treatments, and chronic urinary tract infections (UTIs). The procedure is contraindicated in cases of certain genital structure abnormalities or poor general health.
Circumcision is associated with reduced rates of sexually transmitted infections and urinary tract infections. This includes decreasing the incidence of cancer-causing forms of human papillomavirus (HPV) and significantly reducing HIV transmission among heterosexual men within high risk populations. The World Health Organization (WHO) and UNAIDS recommend circumcision as part of a comprehensive HIV transmission program in areas with high endemic rates of HIV. The WHO does not recommend circumcision for HIV prevention in men who have sex with men; effectiveness of using circumcision to prevent HIV in the developed world is unclear. Neonatal circumcision also decreases the risk of penile cancer. Complication rates are higher when the procedure is performed on older people. A 2010 review found circumcisions performed by medical providers to have a typical complication rate of 1.5% for babies and 6% for older children, with few cases of severe complications. Bleeding, infection, and the removal of either too much or too little foreskin are the most common acute complications. Meatal stenosis is the most common long term complication. Major medical organizations hold variant perspectives on the prophylactic efficacy of the elective circumcision of minors.
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Emasculation is the removal of both the penis and the testicles, the external male sex organs. It differs from castration, which is the removal of the testicles only, although the terms are sometimes used interchangeably. The potential medical consequences of emasculation are more extensive than those associated with castration, as the removal of the penis gives rise to a unique series of complications. There are a range of religious, cultural, punitive, and personal reasons why someone may choose to emasculate themselves or another person.
The Nuba people are indigenous inhabitants of central Sudan. Nuba are various indigenous ethnic groups who inhabit the Nuba Mountains of South Kordofan state in Sudan, encompassing multiple distinct people that speak different languages which belong to at least two unrelated language families. Since 2011, when the southern part of Sudan became an independent state as South Sudan, the Nuba live in the southern part of Sudan. Estimates of the Nuba population vary widely; the Sudanese government estimated that they numbered 2.
The Abrahamic religions are a group of religions centered around the worship of the God of Abraham. Abraham, a Hebrew patriarch, is extensively mentioned throughout the Abrahamic religious scriptures of the Quran, and the Hebrew and Christian Bibles. Jewish tradition claims that the Twelve Tribes of Israel are descended from Abraham through his son Isaac and grandson Jacob, whose sons formed the nation of the Israelites in Canaan (or the Land of Israel); Islamic tradition claims that twelve Arab tribes known as the Ishmaelites are descended from Abraham through his son Ishmael in the Arabian Peninsula.
Congenital malformations or injuries of the urethra can be treated using existing autologous tissue, but these procedures are sometimes associated with severe complications. Therefore, tissue engineering may be advantageous for generating urethral grafts. ...
Elsevier2012
Several urinary tract disorders, such as hypospadias or bladder cancer, require reconstructive surgery to preserve the patient's quality of life and at times even save their life. The current available surgical treatments, involving grafts from other tissu ...