Concept
Gestational hypertension
Related publications (13)
Transcriptomic regulations in oligodendroglial and microglial cells related to brain damage following fetal growth restriction
Yohan Van de Looij, Maxime Olivier Baud
Fetal growth restriction (FGR) is a major complication of human pregnancy, frequently resulting from placental vascular diseases and prenatal malnutrition, and is associated with adverse neurocognitive outcomes throughout life. However, the mechanisms link ...
Wiley-Blackwell2016Structural Brain Connectivity in School-Age Preterm Infants Provides Evidence for Impaired Networks Relevant for Higher Order Cognitive Skills and Social Cognition
Jean-Philippe Thiran, Elda Fischi Gomez, Patric Hagmann, Djalel Eddine Meskaldji, François Lazeyras
Extreme prematurity and pregnancy conditions leading to intrauterine growth restriction (IUGR) affect thousands of newborns every year and increase their risk for poor higher order cognitive and social skills at school age. However, little is known about t ...
Oxford University Press2015Definition and quantification of acute inflammatory white matter injury in the immature brain by MRI/MRS at high magnetic field
Background: Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. The impact of maternal supplementat ...
Nature Publishing Group2014Protective effects of maternal nutritional supplementation with lactoferrin on growth and brain metabolism
Rolf Gruetter, Yohan Van de Looij, Sylviane Métairon
Background:Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. The impact of maternal supplementati ...
Nature Publishing Group2014Does Cancer Start in the Womb? Altered Mammary Gland Development and Predisposition to Breast Cancer due to in Utero Exposure to Endocrine Disruptors
We are now witnessing a resurgence of theories of development and carcinogenesis in which the environment is again being accepted as a major player in phenotype determination. Perturbations in the fetal environment predispose an individual to disease that ...
Springer Verlag2013Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension
Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva
Growing evidence suggests that arginase misregulation plays a key role in the pathophysiology of essential hypertension. In the present study, we investigated the potential cardiovascular therapeutic effects of a long-term treatment with an arginase inhibi ...
Oxford University Press2010The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr
Kristina Schoonjans, Chikage Mataki
Milona A, Owen BM, van Mil S, Dormann D, Mataki C, Boudjelal M, Cairns W, Schoonjans K, Milligan S, Parker M, White R, Williamson C. The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr. Am J P ...
2010Differentiation of Trophoblast Giant Cells and Their Metabolic Functions Are Dependent on Peroxisome Proliferator-Activated Receptor /
Mutation of the nuclear receptor peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) severely affects placenta development, leading to embryonic death at embryonic day 9.5 (E9.5) to E10.5 of most, but not all, PPARbeta/delta-null mutant ...
American Society for Microbiology2006Immunocytochemical expression of monocarboxylate transporters in the human visual cortex at midgestation
Pierre Magistretti, Maxime Olivier Baud, Luc Pellerin
Lactate and the other monocarboxylates are a major energy source for the developing brain. We investigated the immunocytochemical expression of two monocarboxylate transporters, MCT1 and MCT2, in the human visual cortex between 13 and 26 post-ovulatory wee ...
2004Adaptation of conduit artery vascular smooth muscle tone to induced hypertension
Nikolaos Stergiopoulos, Jean-Jacques Meister
We studied the changes in vascular smooth muscle (VSM) cell tone during the adaptation of rat common carotids to induced hypertension. Hypertension was induced in 8 week old male Wistar rats by total ligation of the aorta between the two kidneys. Mean bloo ...
Kluwer Academic Publishers, Springer2002