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Related publications (32)
Control and Characterization of the Compactness of Single-Chain Nanoparticles
Francesco Stellacci, Luciano Andres Abriata, Lixia Wei, Suiyang Liao
Polymers when self-cross-linked into single-chain nanoparticles bear some resemblance to folded proteins; yet proteins have clear energy landscapes that determine precisely folded structures, while single-chain polymer nanoparticles (SCNPs) have more undef ...
AMER CHEMICAL SOC2021Coincidence imaging spectroscopy of extreme-ultraviolet photoionisation processes in molecules and clusters
Presented here is the design, construction and commissioning of a coincidence imaging spectroscopy endstation coupled to the Harmonium high-harmonic generation (HHG) extreme-ultraviolet photon source at the Lausanne Centre for Ultrafast Science. The endsta ...
EPFL2021Architecture of the centriole cartwheel‐containing region revealed by cryo‐electron tomography
Henning Paul-Julius Stahlberg, Paul Guichard, Virginie Hamel
Centrioles are evolutionarily conserved barrels of microtubule triplets that form the core of the centrosome and the base of the cilium. While the crucial role of the proximal region in centriole biogenesis has been well documented, its native architecture ...
2020Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity
Bruno Emanuel Ferreira De Sousa Correia
One of the molecular hallmarks of amyloidoses is ordered protein aggregation involving the initial formation of soluble protein oligomers that eventually grow into insoluble fibrils. The identification and characterization of molecular species critical fo ...
2020Crosslinking Allosteric Sites on the Nucleosome Core Particle
Designing compounds that bind to the acidic patch of the nucleosome core particle (NCP) is an emerging therapeutic approach that can inhibit the binding of key chromatin factors. Pretreatment of human ovarian carcinoma, A2780, cells with RAPTA-T, an antime ...
EPFL2019Histidine Targeting Heterobimetallic Ruthenium(II)-Gold(I) Complexes
Paul Joseph Dyson, Lucinda Kate Batchelor
Inspired by the preferential, allosteric binding of RAPTA-T and auranofin to the nucleosome core particle, we describe the design and synthesis of a series of heterobimetallic ruthenium(II)-gold(I) complexes with varying spacer lengths ranging from four to ...
2019The Structure of the Protonated Serine Octamer
Ursula Röthlisberger, Thomas Rizzo, Stephan Warnke, Marta Andreia Da Silva Perez, Valeriu Scutelnic, Aurelien Stephen Arnaud Gregor, Carsten Baldauf
The amino acid serine has long been known to form a protonated “magic-number” cluster containing eight monomer units that shows an unusually high abundance in mass spectra and has a remarkable homochiral preference. Despite many experimental and theoretica ...
2018A facile synthetic strategy to polysiloxanes containing sulfonyl side groups with high dielectric permittivity
The chemical modification of polymers with lateral polar groups increases their dielectric permittivity above the glass transition temperature, making them attractive materials for dielectric elastomer actuators. Despite the large dipole moment of the sulf ...
Royal Society of Chemistry2017High Permittivity Silicones for Dielectric Elastomer Actuators
Many technical advances of modern society sprout from the creation of specially customized polymer materials exhibiting unique combinations of properties uncharted so far. Amid this plurality of highly versatile materials, the class of electroactive polyme ...
EPFL2017Silicones with enhanced permittivity for dielectric elastomer actuators
The research efforts for silicone based elastomers with high dielectric permittivity (epsilon') intensified significantly in the last years since such materials would allow the construction of dielectric elastomer actuators (DEA) with low operation voltage ...
Spie-Int Soc Optical Engineering2016