Concept

Foreign body reaction

Related publications (44)

Role of macrophage scavenger receptors in atherosclerosis

Accumulating evidence indicates that atherosclerosis is a chronic inflammatory disease. The key innate immune cells that are involved in the pathogenesis of atherosclerosis are circulating monocytes and plaque macrophages. Complex interplay between immune ...

2012

Hybrid Microspheres For Cell Encapsulation

Redouan Mahou

Cell microencapsulation is an active interdisciplinary research field. It requires the input from materials sciences, organic and physical chemistry, biology and medicine. Hydrogels are particularly suitable materials to form microspheres for cell entrapme ...

EPFL2011

Macrophage regulation of tumor angiogenesis: implications for cancer therapy

Michele De Palma, Mario Leonardo Squadrito

This article reviews the evidence for macrophages playing an important role in the regulation of tumor angiogenesis. Findings in mouse models show that macrophages promote angiogenesis in tumors both by producing excessive amounts of proangiogenic factors ...

2011

Controlled release nanoparticle-embedded coatings reduce the tissue reaction to neuroprostheses

Philippe Renaud, André Mercanzini, Philippe Colin, Jeffrey Alan Hubbell, Jean-Charles Bensadoun, Sai Reddy

Controlled release coatings were developed for neuroprostheses with the aim of combating the tissue reaction following implantation in the brain. The coatings consist of poly(propylene sulfide) drug-eluting nanoparticles embedded in a poly(ethylene oxide) ...

Elsevier2010

Augmentation of bone defect healing using a new biocomposite scaffold: an in vivo study in sheep

Dominique Pioletti, Pierre-Etienne Bourban

Previous studies support resorbable biocomposites made of poly L-lactic acid (PLA) and β-tricalcium phosphate (TCP) produced by supercritical gas foaming as a suitable scaffold for tissue engineering. The present study was undertaken to demonstrate the bio ...

Elsevier2010

The effect of lactose-conjugated silk biomaterials on the development of fibrogenic fibroblasts

Boris Hinz

Surface properties of implanted biomaterials can cause fibrotic tissue reactions by stimulating differentiation of host fibroblasts into contractile myofibroblasts. Silk fibroin (SF) protein has been used as biomaterial in pure and blended form. however, i ...

Elsevier2008

Repair of critical size defects in the rat cranium using ceramic-reinforced PLA scaffolds obtained by supercritical gas foaming

Dominique Pioletti, Pierre-Etienne Bourban, Lee Ann Laurent-Applegate

Bioresorbable scaffolds made Of poly(L-lactic acid) (PLA) obtained by supercritical gas foaming were recently described as suitable for tissue engineering, portraying biocompatibility with primary osteoblasts in vitro and interesting mechanical properties ...

2007

Starch-induced implant periapical lesion: A case report

This paper reports an implant periapical lesion (IPL) with a previously unreported etiology. The presence of an osteolytic area around the apex and around the middle portion of a stable Straumann hollow-screw implant was found on periapical radiographs 3.5 ...

2007

Fetal bone cells for tissue engineering

In this thesis, the potential use of fetal bone cells for tissue engineering was evaluated. At first, fetal bone cells were characterized in vitro regarding their proliferation rate, the induction of their osteoblastic phenotype, and their antigenicity. Th ...

EPFL2007

Interaction of Functionalized Superparamagnetic Iron Oxide Nanoparticles with Brain Structures

Heinrich Hofmann, Alke Fink

Super Paramagnetic Iron Oxide Nanoparticles (SPIONs) com-bined with magnetic resonance imaging (MRI) are under clinical evaluation to enhance detection of neurodegenerative diseases. A major improvement would be to link therapeutic drugs to the SPIONs to a ...

2006

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