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We recently identified a novel ribonuclease in Bacillus subtilis called Rae1 that cleaves mRNAs in a translation-dependent manner. Rae1 is a member of the NYN/PIN family of ribonucleases and is highly conserved in the Firmicutes, the Cyanobacteria and the ...
In this article, we explore the use of hackathons and open data in corporations’ open innovation portfolios, addressing a new way for companies to tap into the creativity and innovation of early-stage startup culture, in this case applied to the food and n ...
Big Data is not a new phenomenon. History is punctuated by regimes of data acceleration, characterized by feelings of information overload accompanied by periods of social transformation and the invention of new technologies. During these moments, private ...
This article investigates the TED digital infrastructure for translating Science and Technology projects. Specifically, we seek to investigate the TED infrastructures generative mechanisms and their relation to valuation mechanisms and practices. The resea ...
Mechanical oscillator (10) comprising an inertial body (101) joined to a support (100) by means of an elastic system (102, 103, 104, 105, 106, 107) arranged to provide the inertial body (101) with substantially no degrees of freedom in translation and with ...
Collinear regulation of Hox genes in space and time has been an outstanding question ever since the initial work of Ed Lewis in 1978. Here we discuss recent advances in our understanding of this phenomenon in relation to novel concepts associated with larg ...
Different senses of source words must often be rendered by different words in the target language when performing machine translation (MT). Selecting the correct translation of polysemous words can be done based on the contexts of use. However, state-of-th ...
Re-descriptions: Aldo Rossi’s Architectural Composition. Chair of Architecture and the Public Building, Friday 1 December 2017, Room U 10:45 – 12:30. On the event of the publication in the new issue of OverHolland of the English translation of Ezio Bonfant ...
The PIN domain plays a central role in cellular RNA biology and is involved in processes as diverse as rRNA maturation, mRNA decay and telomerase function. Here, we solve the crystal structure of the Rae1 (YacP) protein of Bacillus subtilis, a founding mem ...
Memory and logic integration on the same chip is becoming increasingly cost effective, creating the opportunity to offload data-intensive functionality to processing units placed inside memory chips. The introduction of memory-side processing units (MPUs) ...