Concept

Longitudinal fissure

Summary
The longitudinal fissure (or cerebral fissure, great longitudinal fissure, median longitudinal fissure, interhemispheric fissure) is the deep groove that separates the two cerebral hemispheres of the vertebrate brain. Lying within it is a continuation of the dura mater (one of the meninges) called the falx cerebri. The inner surfaces of the two hemispheres are convoluted by gyri and sulci just as is the outer surface of the brain. All three meninges of the cortex (dura mater, arachnoid mater, pia mater) fold and descend deep down into the longitudinal fissure, physically separating the two hemispheres. Falx cerebri is the name given to the dura mater in-between the two hemispheres, whose significance arises from the fact that it is the outermost layer of the meninges. These layers prevent any direct connectivity between the bilateral lobes of the cortex, thus requiring any tracts to pass through the corpus callosum. The vasculature of falx cerebri supplies blood to the innermost surfaces of the cortex, neighboring the midsagittal plane. Though this fissure divides the brain, the two hemispheres of the human cortex are not perfectly symmetrical, both in structure and in function. For example, the planum temporale, roughly corresponding to the Wernicke’s area, was found to be 10 times larger in the left than the right hemisphere. In contrast, the caudate nucleus, within the basal ganglia, was found to be larger in the right hemisphere. The corpus callosum connects the two halves of the brain at the bottom of its structure and delivers visual, auditory, and somatosensory messages between each half. Here, billions of neurons and glia can be found working together to send messages that form what is known as the cerebral cortex. The corpus callosum is responsible for eye movement and visual perception, maintaining a balance between arousal and attention, and the ability to identify locations of sensory stimulation. In a clinical setting, those with epilepsy may benefit from the division of the corpus callosum.
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