Retrosynthesis: Basic Principles

This lecture covers the basic principles of retrosynthesis, focusing on protecting groups in organic chemistry. The instructor explains the concept of retrosynthesis, synthesis planning, stereochemistry, and the use of protecting groups to achieve high yields. Different stages of retrosynthesis are discussed, including the selection of disconnections and transformations. The lecture also addresses functional groups, simplification of molecular complexity, and the importance of choosing the right disconnections. Various strategies for selective reductions and the properties of protecting groups are explored, emphasizing their role in organic synthesis.