Partitioning: Equilibrium and Thermodynamics

This lecture covers the concept of partitioning equilibrium, focusing on the distribution of compounds between different phases. It discusses the theoretical background, temperature dependence, and the determination of solubility. The instructor explains the role of chemical potential, standard potentials, and activities of organic compounds in liquid-liquid partitioning. Additionally, the lecture delves into the mechanistic perspective of solubility, molecular interactions affecting solubility, and the formation of cavities in solvents. Various examples and tables are used to illustrate the concepts discussed.