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This lecture by Prof. Marileen Dogterom discusses the construction of minimal microtubule systems in artificial cells, exploring the dynamics and forces involved in building functional microtubule complexity in vitro. The presentation covers topics such as aster positioning, reconstitution of minimal kinetochore particles, and challenges in achieving synthetic cell division. Prof. Dogterom also delves into the interdisciplinary efforts of a multidisciplinary team towards building a synthetic cell, emphasizing the modular and integrative approach required for this endeavor.